Related Experiment Video
Updated: Jan 2, 2026

Transcorporal Artificial Urinary Sphincter Cuff Placement in a Case Requiring Revision for Urethral Atrophy
Published on: June 16, 2022
Transurethral prostate surgery as a preventive method against progression of chronic kidney disease in patients with
Dong Sup Lee1, Hyung Wook Kim2, Seung-Ju Lee3
1Department of Urology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, 93-6 Ji-dong Paldal-gu, Suwon, 16247, Korea.
Objective:
The present study was aimed to investigate (1) whether urodynamic factors are responsible for kidney damage in patients with bladder outlet obstruction (BOO) and (2) whether transurethral prostate surgery for BOO can alleviate the damage to the kidneys.
Methods:
This prospective observational study involved men aged 50-80 years. Prostate size and urodynamic test were performed during screening period. Laboratory tests to measure the glomerular filtration rate, the urinary protein to creatinine ratio and dipstick urinalysis were performed before and 6 months after the transurethral prostate surgery.
Results:
Sixty-seven patients completed the laboratory study among a hundred enrolled patients with urodynamically proven BOO. Among the urodynamic parameters, only low bladder compliance (lower than 60 mL/cmH2O) was associated with clinically significant proteinuria (p < 0.001). Transurethral prostate surgery significantly improved proteinuria (p = 0.007), especially in patients with low bladder compliance (p = 0.004), and subsequently decreased the risk grade of CKD progression (p < 0.001).
Conclusions:
Low bladder compliance in patients with BOO may be a risk factor for kidney damage. Transurethral prostate surgery to relieve BOO could be a preventive method against CKD progression in patients with low bladder compliance.
Related Concept Videos
Urinary Tract Calculi VI: Surgical Management
Kidney Transplant II: Surgical Procedure
Urinary Tract Calculi III: Medical Management
Imaging Studies V: Intravenous Urography and Retrograde Pyelography
Urinary Tract Calculi IV: Nutrition Therapy and Prevention
Urologic Endoscopic Procedure: Cystoscopic Examination

