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Author Spotlight: Insights into Cardiometabolic Diseases with Subcutaneous Adipose Tissue Microvasculature Studies
Published on: April 5, 2024
Bridging the Gap for Patients with Diabetes and Cardiovascular Disease Through Cardiometabolic Collaboration
Lee-Shing Chang1, Muthiah Vaduganathan2, Jorge Plutzky2
1Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital, 221 Longwood Avenue, RFB-2, Boston, MA, 02115, USA. lchang12@bwh.harvard.edu.
Purpose Of Review:
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in individuals with type 2 diabetes (T2D). Recent cardiovascular outcome trials (CVOTs) have established sodium-glucose co-transporter-2 inhibitors (SGLT2i) and glucagon-like peptide-1 receptor agonists (GLP1 RA) as powerful medications that can lower glucose as well as reduce the risk of complications of CVD in many individuals with T2D. The combination of glycemic and cardiovascular benefits of SGLT2i and GLP1 RA has highlighted the importance of collaborative care of patients by diabetes and cardiovascular specialists. We review several models of cardiometabolic care for patients with diabetes and CVD and discuss practical ways in which diabetes and cardiovascular specialists can work together to improve cardiometabolic care.
Recent Findings:
CVOTs for SGLT2i and GLP1 RA have demonstrated a significant reduction in major adverse cardiovascular events in individuals with T2D and CVD, in addition to their beneficial effects on glucose lowering and weight loss. Additionally, several models of care, including population health screening models with or without a remote management intervention, multidisciplinary clinics, and combined cardiometabolic training, have been proposed to better facilitate the multifaceted care that individuals with diabetes and CVD require. Innovative models of cardiometabolic care have the potential to improve the quality of care that individuals with diabetes and CVD receive. Through collaboration and co-management, diabetes specialists, cardiovascular specialists, and primary care providers have the ability to optimize diabetes and cardiovascular care.
Insights
Sodium-glucose co-transporter-2 inhibitors (SGLT2i) and glucagon-like peptide-1 receptor agonists (GLP1 RA) reduce cardiovascular risk in type 2 diabetes (T2D). Collaborative care models improve management for patients with T2D and cardiovascular disease (CVD).
Area of Science:
- Cardiology
- Endocrinology
- Metabolic Diseases
Background:
- Cardiovascular disease (CVD) is a primary cause of death in type 2 diabetes (T2D).
- Sodium-glucose co-transporter-2 inhibitors (SGLT2i) and glucagon-like peptide-1 receptor agonists (GLP1 RA) offer significant cardiovascular benefits beyond glucose control in T2D patients.
Purpose of the Study:
- To review current models of cardiometabolic care for patients with diabetes and CVD.
- To discuss collaborative strategies between diabetes and cardiovascular specialists for improved patient outcomes.
Main Methods:
- Review of recent cardiovascular outcome trials (CVOTs) for SGLT2i and GLP1 RA.
- Analysis of proposed and existing models of cardiometabolic care.
Main Results:
- SGLT2i and GLP1 RA significantly reduce major adverse cardiovascular events in T2D patients.
- Various care models, including multidisciplinary clinics and remote management, enhance care for complex patients.
- Collaboration between specialists optimizes diabetes and cardiovascular care.
Conclusions:
- Innovative cardiometabolic care models can enhance the quality of care for individuals with T2D and CVD.
- Co-management by diabetes specialists, cardiovascular specialists, and primary care providers is crucial for optimizing patient management.
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Assessment:
