Resisting resistance: gearing up for war
Aurijit Sarkar1, Sylvie Garneau-Tsodikova2
1Fred Wilson School of Pharmacy , High Point University , One University Pkwy , High Point , NC 27268 , USA .
Medchemcomm
|December 6, 2019
Summary
Antimicrobial resistance (AMR) threatens our ability to treat infections from drug-resistant bacteria, fungi, and parasites. A united societal effort is crucial to develop new treatments and overcome this global health crisis.
Area of Science:
- Microbiology
- Infectious Diseases
- Public Health
Background:
- Antimicrobial resistance (AMR) is a growing global health threat.
- Multidrug-resistant (MDR) and extended drug-resistant (XDR) pathogens are emerging, reducing treatment options.
- Existing antimicrobials are at risk of losing clinical efficacy against a wide range of pathogens.
Purpose of the Study:
- To assess the current standing in the fight against AMR.
- To issue a call to action for all stakeholders involved in combating AMR.
- To identify key challenges and highlight positive developments in AMR research and control.
Main Methods:
- This is an opinion piece, not a research study.
- It synthesizes current knowledge and expert perspectives on AMR.
- It analyzes past successes and failures in infectious disease control.
Main Results:
- The efficacy of many antimicrobials is declining due to resistance.
- A comprehensive, societal approach is necessary to combat AMR.
- Learning from historical public health campaigns is essential for future strategies.
Conclusions:
- Urgent, collaborative action is required to address the AMR crisis.
- A multi-faceted strategy, incorporating lessons learned, is vital for future success.
- Winning the war against AMR necessitates a proactive and unified global response.
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