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Resisting resistance: gearing up for war

Aurijit Sarkar1, Sylvie Garneau-Tsodikova2

  • 1Fred Wilson School of Pharmacy , High Point University , One University Pkwy , High Point , NC 27268 , USA .

Medchemcomm
|December 6, 2019
PubMed

Insights

Antimicrobial resistance (AMR) threatens our ability to treat infections from drug-resistant bacteria, fungi, and parasites. A united societal effort is crucial to develop new treatments and overcome this global health crisis.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Public Health

Background:

  • Antimicrobial resistance (AMR) is a growing global health threat.
  • Multidrug-resistant (MDR) and extended drug-resistant (XDR) pathogens are emerging, reducing treatment options.
  • Existing antimicrobials are at risk of losing clinical efficacy against a wide range of pathogens.

Purpose of the Study:

  • To assess the current standing in the fight against AMR.
  • To issue a call to action for all stakeholders involved in combating AMR.
  • To identify key challenges and highlight positive developments in AMR research and control.

Main Methods:

  • This is an opinion piece, not a research study.
  • It synthesizes current knowledge and expert perspectives on AMR.
  • It analyzes past successes and failures in infectious disease control.

Main Results:

  • The efficacy of many antimicrobials is declining due to resistance.
  • A comprehensive, societal approach is necessary to combat AMR.
  • Learning from historical public health campaigns is essential for future strategies.

Conclusions:

  • Urgent, collaborative action is required to address the AMR crisis.
  • A multi-faceted strategy, incorporating lessons learned, is vital for future success.
  • Winning the war against AMR necessitates a proactive and unified global response.

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