Related Experiment Video
Updated: Jan 2, 2026

04:37
Author Spotlight: Integrating Mechanical and Biological Analysis in Tendinopathy Research
Published on: March 1, 2024
1.3K
PAIN SENSITIVITY IN CHRONIC ACHILLES TENDINOPATHY
Brian J Eckenrode, David M Kietrys1, Scott K Stackhouse2
1Rutgers School of Health Professions, Blackwood, NJ, USA.
International Journal of Sports Physical Therapy
|December 6, 2019
Summary
Chronic Achilles tendinopathy in athletes shows signs of both peripheral and central nervous system sensitization. This suggests that physical therapy for tendinopathy should address these nervous system changes.
Area of Science:
- Sports Medicine
- Pain Research
- Neurology
Background:
- Achilles tendinopathy is a prevalent overuse injury in athletes, frequently becoming chronic.
- Chronic musculoskeletal pain conditions often display signs of nervous system sensitization.
Purpose of the Study:
- To compare pain sensitivity, including pressure pain threshold (PPT), heat pain threshold (HPT), and heat temporal summation (HTS), between athletes with and without chronic Achilles tendinopathy.
- To investigate the presence of peripheral and/or central sensitization in chronic Achilles tendinopathy.
Main Methods:
- A cohort study involving 17 participants with chronic Achilles tendinopathy (≥3 months) and 24 healthy controls.
- Pain processing was assessed using PPT, HPT, and HTS tests.
- Participants completed questionnaires including the Pain Catastrophizing Scale (PCS), Lower Extremity Functional Scale (LEFS), and Victorian Institute of Sport Assessment-Achilles (VISA-A).
Main Results:
- Participants with Achilles tendinopathy exhibited primary hyperalgesia (lower PPT and HPT) at the injury site.
- Mechanical secondary hyperalgesia, indicative of central sensitization, was observed in the affected leg and tibialis anterior muscle.
- No significant differences in PCS scores or HTS were found between the groups.
Conclusions:
- Active individuals with chronic Achilles tendinopathy demonstrate signs of both peripheral and central sensitization.
- These findings support a multifactorial model of tendinopathy involving motor, local, and pain system components.
- Physical therapy interventions for chronic Achilles tendinopathy may need to incorporate strategies to address nervous system sensitization.
More Related Videos
Related Concept Videos
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
296
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
296
Analgesia and Pain Management
1.4K
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
1.4K
Pain
1.2K
Pain serves as a critical warning signal that alerts the body to potential or actual harm. When mechanical pressure on the skin is intense, such as from a sharp pinch, the sensation transitions from touch to pain. Similarly, extreme temperatures, like a hot pot handle, convert the sensation of heat into pain. Pain can also result from overstimulation of other senses, such as blinding light, loud noise, or the intense heat from habañero peppers. This ability to sense pain is essential for...
1.2K

