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Updated: Jan 2, 2026

Author Spotlight: Therapeutic Benefit of Closed-Loop Deep Brain Stimulation in Depression Treatment
Published on: July 7, 2023
Rebecca E Salomon1, Jamie Crandell, Keely A Muscatell
1Rebecca E. Salomon, PhD, RN, PMHNP-BC, is Postdoctoral Fellow, University of California San Francisco School of Nursing. At the time this research was completed, she was a Predoctoral Trainee at the University of North Carolina at Chapel Hill School of Nursing. Jamie Crandell, PhD, is Research Assistant Professor, University of North Carolina at Chapel Hill School of Nursing and Department of Biostatistics, Gillings School of Global Public Health, Chapel Hill, North Carolina. Keely A. Muscatell, PhD, is Assistant Professor, Department of Psychology and Neuroscience, College of Arts and Sciences, University of North Carolina at Chapel Hill, with a dual appointment at the Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina. Hudson P. Santos, Jr., PhD, RN, is Assistant Professor; Ruth A. Anderson, PhD, RN, FAAN, is the Kenan Distinguished Professor and Associate Dean for Research; and Linda S. Beeber, PhD, PMHCNS-BC, FAAN, is Professor and Assistant Dean, PhD Division and PhD Program, University of North Carolina at Chapel Hill School of Nursing.
Composite scoring simplifies symptom clusters but may lose data variation. Reduced rank regression offers a nuanced approach, identifying key symptoms like pain and depressed mood impacting mothers' function.
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