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Prevalence and risk factors of overactive bladder in Chinese children: A population-based study
Dong Xing1,2, Yi He Wang1,2, Yi Bo Wen1,2
1Pediatric Urodynamic Centre, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Insights
Overactive bladder (OAB) affects 9.01% of Chinese children aged 5-14, with prevalence decreasing with age. Risk factors include obesity, UTIs, and late elimination communication (EC) start.
Area of Science:
- Pediatrics
- Urology
- Public Health
Background:
- Overactive bladder (OAB) is a common condition in children, impacting quality of life.
- Understanding OAB prevalence and risk factors in specific populations is crucial for targeted interventions.
Purpose of the Study:
- To determine the prevalence of overactive bladder (OAB) in Chinese children aged 5 to 14 years.
- To identify risk factors associated with OAB in this pediatric population.
Main Methods:
- A cross-sectional study involving 10,133 children aged 5-14 in five Chinese provinces.
- Anonymous, self-administered questionnaires collected data on demographics, urinary tract infections (UTIs), lower urinary tract symptoms (LUTS), family history, bowel symptoms, and elimination communication (EC) start time.
Main Results:
- The overall prevalence of OAB was 9.01%, decreasing with age (12.40% at 5 years to 4.55% at 14 years).
- Late-onset EC, obesity, history of UTI, nocturnal enuresis (NE), family history of LUTS, constipation, and fecal incontinence were associated with higher OAB prevalence.
Conclusions:
- Obesity, UTI history, NE, family history of LUTS, and bowel symptoms are significant risk factors for childhood OAB.
- Initiating elimination communication (EC) before 12 months of age may help reduce OAB prevalence in children.
Aims:
To investigate the prevalence of overactive bladder (OAB) and assess its risk factors in 5- to 14-year-old Chinese children.
Methods:
A cross-sectional study of OAB prevalence was performed by distributing 11 800 anonymous self-administered questionnaires to parents in five provinces of mainland China from July to October 2018. The questionnaires included questions on sociodemographics, history of urinary tract infection (UTI), lower urinary tract symptoms (LUTS), family history of LUTS, bowel symptoms, and details about the elimination communication (EC) start time. OAB was defined as urgency and increased the daytime frequency with or without urinary incontinence.
Results:
A total of 10 133 questionnaires qualified for statistical analysis. The overall prevalence of OAB was 9.01% and decreased with age, from 12.40% at 5 years to 4.55% at 14 years (χ2 trend = 88.899; P < .001). The proportion of dry OAB increased with age, whereas the proportion of wet OAB decreased. A late-onset of EC was associated with a high OAB prevalence (χ2 trend = 39.802; P < .001). Children with obesity, a history of UTI, nocturnal enuresis (NE), a family history of LUTS, constipation, and fecal incontinence had a higher prevalence of OAB than did normal children (P < .05).
Conclusion:
Obesity, a history of UTI, NE, a family history of LUTS, and bowel symptoms are risk factors associated with OAB. Starting EC before 12 months of age might help reduce the prevalence of OAB in children.
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