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Updated: Jan 2, 2026

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An In vitro Model to Study Heterogeneity of Human Macrophage Differentiation and Polarization
Published on: June 12, 2013
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Connecting Transcriptional and Functional Macrophage Heterogeneity in Atherosclerosis
Martin Schlegel1, Graeme J Koelwyn1, Kathryn J Moore1
1From the Department of Medicine, Marc and Ruti Bell Program for Vascular Biology and Disease, The Leon H. Charney Division of Cardiology, New York University School of Medicine.
Circulation Research
|December 6, 2019
Abstract
No abstract available in PubMed .
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Atherosclerosis is a progressive disorder characterized by the buildup of plaques on the arterial inner wall, causing them to narrow and harden over time. These plaques comprise lipids, calcium, blood components, carbohydrates, and fibrous tissue. The process primarily affects the intima of large and medium-sized arteries, reducing blood flow in any artery.Etiology and risk factorsThe cause of atherosclerosis is multifactorial, involving a complex interplay among endothelial injury, lipid...
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