Related Experiment Video

Updated: Jan 2, 2026

Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography
03:47

Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography

Published on: November 1, 2024

365

Relationship between heart failure and central serous chorioretinopathy: A cohort study in Taiwan

Ke-Hao Huang1,2, Yi-Hao Chen1, Lung-Chi Lee1

  • 1Department of Ophthalmology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC.

Journal of the Chinese Medical Association : JCMA
|December 6, 2019
PubMed

Insights

Heart failure (HF) significantly increases the risk of central serous chorioretinopathy (CSCR). Patients with HF should monitor for visual impairment, as this study found a strong association between the two conditions.

Area of Science:

  • Ophthalmology
  • Cardiology
  • Public Health

Background:

  • Central serous chorioretinopathy (CSCR) and heart failure (HF) have complex, potentially shared, pathogenetic mechanisms.
  • This study investigated the potential risk of CSCR in patients diagnosed with HF.

Purpose of the Study:

  • To evaluate the association between heart failure (HF) and the risk of developing central serous chorioretinopathy (CSCR).
  • To identify potential risk factors and quantify the increased incidence of CSCR in HF patients.

Main Methods:

  • Utilized the National Health Insurance Research Database (NHIRD) for a 14-year period.
  • Employed Pearson chi-square and Fisher's exact tests for variable analysis.
  • Assessed risk factors using adjusted hazard ratios (aHR) and Kaplan-Meier analysis for cumulative incidence.

Main Results:

  • A cohort of 24,426 HF patients and 24,426 controls was analyzed.
  • HF patients exhibited a significantly higher incidence rate of CSCR (aHR = 4.572, p < 0.001).
  • Increased CSCR risk was observed across all genders and age groups in HF patients.

Conclusions:

  • Heart failure (HF) is identified as a significant risk indicator for central serous chorioretinopathy (CSCR).
  • Patients with HF require heightened awareness regarding potential visual impairment.
  • Further prospective research is recommended to elucidate the HF-CSCR relationship.
Abstract

More Related Videos

Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography03:35

Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography

Published on: December 1, 2023

562
A Surgical Model of Heart Failure with Preserved Ejection Fraction in Tibetan Minipigs07:09

A Surgical Model of Heart Failure with Preserved Ejection Fraction in Tibetan Minipigs

Published on: February 18, 2022

2.2K

Related Concept Videos

Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
624
Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
2.6K
Heart Failure I: Introduction01:27

Heart Failure I: Introduction

Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
626
Heart Failure IV: Classification and Diagnostic Evaluation01:30

Heart Failure IV: Classification and Diagnostic Evaluation

Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
261
Heart Failure III: Clinical Manifestations01:26

Heart Failure III: Clinical Manifestations

Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
397
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
408