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False negative findings at third trimester chorionic villus sampling (C.V.S.)
N J Leschot1, H Wolf, G H Weenink
1Department of Human Genetics, University of Amsterdam, The Netherlands.
Clinical Genetics
|September 1, 1988
A discrepancy is reported between the karyotypes of chorionic cells (direct method):46,XX and of cultured amniotic fluid cells: 47,XX, + 18 in a pregnancy of 30 weeks. A stillborn girl, with external signs of trisomy 18 syndrome, was subsequently shown to have a mosaic pattern in both the lymphocytes and the placenta.
A discrepancy is reported between the karyotypes of chorionic cells (direct method):46,XX and of cultured amniotic fluid cells: 47,XX, + 18 in a pregnancy of 30 weeks. A stillborn girl, with external signs of trisomy 18 syndrome, was subsequently shown to have a mosaic pattern in both the lymphocytes and the placenta.