A three-year experience with CCPD in a university-based dialysis and transplantation program
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W D Mattern1, C R Morris, D L Heffley
1Department of Medicine, University of North Carolina, Chapel Hill 27514.
Insights
Continuous Cyclic Peritoneal Dialysis (CCPD) is effective for pediatric End-Stage Renal Disease (ESRD) patients awaiting transplantation. It is also a viable alternative for adult dialysis patients, particularly those with diabetes or cardiovascular issues.
Area of Science:
- Nephrology
- Pediatric Nephrology
- Renal Replacement Therapy
Background:
- Continuous Cyclic Peritoneal Dialysis (CCPD) offers a home-based dialysis modality.
- This study evaluates CCPD over three years in a university-based program.
- Patient demographics included infants, children, and adults, with a subset of diabetic adults.
Observation:
- CCPD was initiated in 51 patients between March 1984 and February 1987.
- The patient cohort comprised 5 infants (<3 years), 11 children (3-17 years), and 35 adults (8 with diabetes mellitus).
- Treatment selection approaches and outcomes, including peritonitis rates, were analyzed across age groups.
Findings:
- CCPD is the preferred treatment for pediatric ESRD patients awaiting kidney transplantation.
- For adults, CCPD is a reasonable alternative dialysis modality.
- It is particularly suitable for elderly patients, those with diabetes mellitus, and individuals with severe cardiovascular disease who prefer home-based treatment or tolerate hemodialysis poorly.
Implications:
- CCPD is a crucial and increasingly utilized renal replacement therapy for specific pediatric and adult patient populations.
- The findings support CCPD as a valuable option for improving quality of life and treatment adherence in ESRD management.
- The growing prevalence of suitable adult candidates highlights the expanding role of CCPD in nephrology practice.
Abstract:
A three-year experience with CCPD in adults and children in a university-based Dialysis and Transplantation Program is presented. Fifty-one patients began treatment from March of 1984 through February of 1987 (5 infants less than age three years, 11 children ages 3 to 17 years and 35 adults, of whom 8 had diabetes mellitus). The approach to treatment selection and the results of treatment including peritonitis rates and patient outcomes are described in the different groups. CCPD has become the treatment of choice for infants and children with ESRD awaiting kidney transplantation. In adults it is a considered a reasonable alternative, and may be the preferred dialysis, modality, in elderly patients, patients with diabetes mellitus and patients with severe cardiovascular disease who require or prefer assistance, who wish to be at home, and who tolerate hemodialysis poorly. This segment of the dialysis population appears to be increasing steadily.