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Cell Bioprinting: The 3D-Bioplotter™ Case
David Angelats Lobo1,2, Paola Ginestra1
1Department of Mechanical and Industrial Engineering, University of Brescia, V. Branze 38, 25123 Brescia, Italy.
Materials (Basel, Switzerland)
|December 8, 2019
Summary
Three-dimensional (3D) bioprinting uses biomaterials and cells to create complex structures, overcoming limitations of traditional cell cultures. This review synthesizes information on 3D bioprinting technologies and applications, particularly the 3D-Bioplotter™, to aid researchers.
Area of Science:
- Biotechnology
- Regenerative Medicine
- Materials Science
Background:
- Traditional 2D cell culture lacks physiological relevance.
- Three-dimensional (3D) bioprinting offers a more biomimetic approach using biopolymers and cells.
- Existing literature presents fragmented information, hindering research reproducibility.
Purpose of the Study:
- To consolidate available information on 3D bioprinting techniques and challenges.
- To provide a comprehensive overview for researchers navigating 3D bioprinting.
- To highlight the capabilities and applications of specific technologies like the 3D-Bioplotter™.
Main Methods:
- Comprehensive literature review of 3D bioprinting research.
- Analysis of the capabilities and applications of the 3D-Bioplotter™.
- Discussion of advancements towards 4D bioprinting.
Main Results:
- 3D bioprinting enables the creation of intricate structures with multiple materials.
- The 3D-Bioplotter™ offers precision, flexibility, and user-friendly software for optimizing bioprinting.
- Applications are primarily in regenerative medicine, but reproducibility issues persist due to information gaps.
Conclusions:
- 3D bioprinting significantly advances cell culture and regenerative medicine.
- Addressing information fragmentation is crucial for enhancing reproducibility in 3D bioprinting research.
- The emerging field of 4D bioprinting holds promise for future innovations.
