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Azidothymidine-induced depression of murine hemopoietic progenitor cells
G Bogliolo1, R Lerza, M Mencoboni
1Istituto Scientifico di Medicina Interna, University of Genoa, Italy.
Experimental Hematology
|December 1, 1988
Abstract:
The toxicity of the antiviral drug 3'-azido-3'-deoxythymidine was studied in vivo on murine hemopoietic progenitor cells and peripheral blood cells. The drug induced a marked decrease of all tested populations, showing a severe toxicity on hemopoiesis.