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Past, Present and Future of Flow Cytometry in Breast Cancer - A Systematic Review

Maria Andreou1, Evrysthenis Vartholomatos1, Haralampos Harissis2

  • 1Haematology Laboratory-Unit of Molecular Biology, University Hospital of Ioannina, Greece.

EJIFCC
|December 10, 2019
PubMed

Keywords:
aneuploidybreast cancerflow cytometry

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The development of flow cytometry techniques began in 1934 with initial attempts by Andrew Moldavan, a bacteriologist who counted the cells in a flowing capillary system. Moldavan pumped cells through a capillary tube focused under a microscope for visualization. The invention of photometry allowed the measurement of differentially-stained cells, and Louis Kamentsky developed the first multiparameter flow cytometer in 1965 to identify and count the cancer cells in cervical tissue specimens.
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