[Disorders of the endothelial pavement of the vascular bed caused by denervation]

The changes of endothelial surface in a tail artery at its denervation provoked by the removal of a part of adventitia have been studied with the help of scanning electron microscopy. It has been shown that the innervation didn't occur in a distal part of a vessel 10-days after the operation, there were considerable changes in the endothelial cover resulting in the protrusion of nuclear region of endothelial cells into the vessel lumen and in occurrence of spindle-like cells with long, thin projections while in the proximal part of the vessel the innervation was retaining, the endothelial surface changes being not significant. It can be concluded that the endothelial surface change is due to the switching off vascular nerve influences on a vascular wall, being not result of a postoperative injury.