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Related Experiment Videos

Esophageal candidiasis.

Y Naito1, T Yoshikawa, H Oyamada

  • 1First Department of Internal Medicine, Kyoto Prefectural University of Medicine, Japan.

Gastroenterologia Japonica
|August 1, 1988
PubMed
Summary

Esophageal candidiasis affects individuals with weakened immunity, including those with malignancies or diabetes. Early detection through endoscopy is crucial to prevent invasive fungal infections, especially in immunocompromised patients.

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Area of Science:

  • Gastroenterology
  • Infectious Diseases
  • Oncology

Background:

  • Esophageal candidiasis is a fungal infection of the upper digestive tract.
  • It often affects individuals with compromised immune systems.

Purpose of the Study:

  • To determine the prevalence of esophageal candidiasis in patients undergoing upper digestive tract endoscopy.
  • To identify risk factors and associated conditions for esophageal candidiasis.

Main Methods:

  • Endoscopic examination of the upper digestive tract.
  • Diagnosis via esophageal brushing or histological examination of biopsy specimens.

Main Results:

  • Out of 3,501 individuals, 41 cases of esophageal candidiasis were identified.

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  • Associated conditions included malignancies (17), immunological disorders (14), diabetes mellitus (4), and other diseases (7).
  • Systemic fungal invasion was noted in patients with hematologic malignancies, often treated with immunosuppressants.

    • Conclusions:

    • Patients with malignancy and impaired immunity require careful screening for esophageal candidiasis to prevent invasive disease.
    • Reduced gastric acidity, potentially due to H2 blockers, may be a contributing factor to esophageal candidiasis.