Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

AI-based imputation of anti-Müllerian hormone enables robust prediction of oocyte retrieval during controlled ovarian stimulation.

Journal of assisted reproduction and genetics·2026
Same author

Visual Indicator for Intradialytic Hypotension Prediction Using Variation and Compensation of Heart Rate.

Diagnostics (Basel, Switzerland)·2024
Same author

Unleashing the potential of natural protein based nanoparticles for the delivery of therapeutic nucleic Acid: A comprehensive review.

International journal of pharmaceutics·2024
Same author

A Preliminary Study on Kinetic Analysis of Ground Reaction Force and Impulse During Gait in Patients With Total Hip Replacement and Implication for Rehabilitation.

Orthopaedic surgery·2024
Same author

GloGen: PPG prompts for few-shot transfer learning in blood pressure estimation.

Computers in biology and medicine·2024
Same author

Mechanical energy fluctuation in lower limbs during walking in participants with and without total hip replacement.

Royal Society open science·2023

Related Experiment Video

Updated: Jan 2, 2026

Microfluidic Mixers for Studying Protein Folding
12:42

Microfluidic Mixers for Studying Protein Folding

Published on: April 10, 2012

15.5K

Asymmetrical Split-and-Recombine Micromixer with Baffles.

Wasim Raza1, Kwang-Yong Kim1

  • 1Department of Mechanical Engineering, Inha University, Incheon 22212, Korea.

Micromachines
|December 11, 2019
PubMed
Summary

This study introduces a novel planar micromixer design that significantly enhances mixing efficiency. The hybrid design achieves over 90% mixing index at Reynolds numbers of 20 and above, outperforming previous models.

Keywords:
Navier–Stokes equationsbafflesmicromixersmixing indexparametric studyunbalanced split-and-recombination

More Related Videos

One-Step Approach to Fabricating Polydimethylsiloxane Microfluidic Channels of Different Geometric Sections by Sequential Wet Etching Processes
08:31

One-Step Approach to Fabricating Polydimethylsiloxane Microfluidic Channels of Different Geometric Sections by Sequential Wet Etching Processes

Published on: September 13, 2018

10.3K
Quantifying Mixing using Magnetic Resonance Imaging
07:33

Quantifying Mixing using Magnetic Resonance Imaging

Published on: January 25, 2012

11.3K

Related Experiment Videos

Last Updated: Jan 2, 2026

Microfluidic Mixers for Studying Protein Folding
12:42

Microfluidic Mixers for Studying Protein Folding

Published on: April 10, 2012

15.5K
One-Step Approach to Fabricating Polydimethylsiloxane Microfluidic Channels of Different Geometric Sections by Sequential Wet Etching Processes
08:31

One-Step Approach to Fabricating Polydimethylsiloxane Microfluidic Channels of Different Geometric Sections by Sequential Wet Etching Processes

Published on: September 13, 2018

10.3K
Quantifying Mixing using Magnetic Resonance Imaging
07:33

Quantifying Mixing using Magnetic Resonance Imaging

Published on: January 25, 2012

11.3K

Area of Science:

  • Fluid dynamics
  • Microfluidics
  • Chemical engineering

Background:

  • Micromixers are crucial for efficient fluid manipulation in microfluidic devices.
  • Traditional split-and-recombine micromixers often face limitations in mixing performance across various flow regimes.
  • Developing advanced micromixer designs is essential for improving reaction rates and process efficiency in microscale applications.

Purpose of the Study:

  • To propose and numerically evaluate a novel planar micromixer design.
  • To investigate the mixing performance of a hybrid micromixer incorporating split-and-recombine units and curved channels with radial baffles.
  • To analyze the impact of geometrical parameters on the mixing efficiency of the proposed micromixer.

Main Methods:

  • Numerical simulation using continuity, momentum, and advection-diffusion equations.
  • Evaluation of mixing performance based on the variance of concentration and mixing index.
  • Systematic analysis across a Reynolds number range of 0.1 to 80.
  • Parametric study of three key geometrical features influencing mixing.

Main Results:

  • The proposed hybrid micromixer demonstrates superior mixing performance compared to conventional split-and-recombine designs.
  • High mixing indices, exceeding 90%, were achieved for Reynolds numbers greater than or equal to 20.
  • A maximum mixing index of 99.8% was recorded at a Reynolds number of 80.
  • Over 80% mixing was attained within 63% of the device length at a Reynolds number of 20.

Conclusions:

  • The hybrid micromixer design offers significantly enhanced mixing capabilities across a wide range of Reynolds numbers.
  • The integration of split-and-recombine modules with curved channels and radial baffles is an effective strategy for improving microfluidic mixing.
  • The findings provide valuable insights for the optimization of microfluidic devices requiring efficient mixing for various applications.