Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Multi-input and Multi-variable systems01:22

Multi-input and Multi-variable systems

351
Cruise control systems in cars are designed as multi-input systems to maintain a driver's desired speed while compensating for external disturbances such as changes in terrain. The block diagram for a cruise control system typically includes two main inputs: the desired speed set by the driver and any external disturbances, such as the incline of the road. By adjusting the engine throttle, the system maintains the vehicle's speed as close to the desired value as possible.
In the absence of...
351
One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation01:24

One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation

1.1K
This lesson introduces two critical methods in pharmacokinetics, the Wagner-Nelson and Loo-Riegelman methods, used for estimating the absorption rate constant (ka) for drugs administered via non-intravenous routes. The Wagner-Nelson method relates ka to the plasma concentration derived from the slope of a semilog percent unabsorbed time plot. However, it is limited to drugs with one-compartment kinetics and can be impacted by factors like gastrointestinal motility or enzymatic degradation.
On...
1.1K
Sampling Methods: Overview01:06

Sampling Methods: Overview

2.0K
A sample refers to a smaller subset representative of a larger population. In analytical chemistry, studying or analyzing an entire population is often impractical or impossible. Therefore, samples are used to draw inferences and generalize the whole population. The sampling method selects individuals or items from a population to create a sample. Standard sampling methods include random, judgemental, systematic, stratified, and cluster sampling. 
In analytical chemistry, the choice of...
2.0K
Cluster Sampling Method01:20

Cluster Sampling Method

13.9K
Appropriate sampling methods ensure that samples are drawn without bias and accurately represent the population. Because measuring the entire population in a study is not practical, researchers use samples to represent the population of interest.
To choose a cluster sample, divide the population into clusters (groups) and then randomly select some of the clusters. All the members from these clusters are in the cluster sample. For example, if you randomly sample four departments from your...
13.9K
Systematic Sampling Method01:17

Systematic Sampling Method

12.4K
Sampling is a technique to select a portion (or subset) of the larger population and study that portion (the sample) to gain information about the population. Data are the result of sampling from a population. The sampling method ensures that samples are drawn without bias and accurately represent the population. Because measuring the entire population in a study is not practical, researchers use samples to represent the population of interest.
Systematic sampling is one of the simplest methods...
12.4K
Extraction: Partition and Distribution Coefficients01:14

Extraction: Partition and Distribution Coefficients

4.5K
The distribution law or Nernst's distribution law is the law that governs the distribution of a solute between two immiscible solvents. This law, also known as the partition law, states that if a solute is added to the mixture of two immiscible solvents at a constant temperature, the solute is distributed between the two solvents in such a way that the ratio of solute concentrations in the solvents remains constant at equilibrium.
For extracting a solute from an aqueous phase into an...
4.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Longitudinal Associations Between Inflammation and Multi-Dimensional Fatigue up to 2 Years After Colorectal Cancer Diagnosis.

International journal of cancer·2026
Same author

Manganese-based cathode materials for aqueous zinc-ion batteries: a mini review.

Nanoscale·2026
Same author

Detection of rare medical events in electronic health records using machine learning: Current practices and suggestions - A scoping review.

PloS one·2026
Same author

Exploratory structural equation modeling and the curse of dimensionality.

Behavior research methods·2026
Same author

Effects of Cancer Treatment on Inflammation in Colorectal Cancer Patients: A Longitudinal Study.

Clinical colorectal cancer·2026
Same author

Development and validation of an interpretable machine learning model for retrospective identification of suspected infection for sepsis surveillance: a multicentre cohort study.

EClinicalMedicine·2025
Same journal

Correction: A method for supervoxel-wise association studies of age and other non-imaging variables from coronary computed tomography angiograms.

Scientific reports·2026
Same journal

Poly(bromophenol blue)/CoSn(OH)<sub>6</sub> cubic particles modified pencil graphite electrode for electrochemical determination of diphenhydramine.

Scientific reports·2026
Same journal

Dietary Chlorella, Spirulina, and acidifier modulate jejunal cytokine-related gene expression in broiler chickens.

Scientific reports·2026
Same journal

Perceived physical activity barriers in university students: associations with fatigue and eating behaviours.

Scientific reports·2026
Same journal

Refuge limitation structures habitat use in agricultural landscapes: evidence from Sunda pangolins.

Scientific reports·2026
Same journal

Lightweight stateless transaction verification with outsourced witness updates for UTXO blockchains.

Scientific reports·2026
See all related articles

Related Experiment Video

Updated: Jan 2, 2026

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K

Variable Selection in the Regularized Simultaneous Component Analysis Method for Multi-Source Data Integration.

Zhengguo Gu1, Niek C de Schipper2, Katrijn Van Deun2

  • 1Department of Methodology and Statistics, Tilburg University, Tilburg, 5000, LE, The Netherlands. z.gu@tilburguniversity.edu.

Scientific Reports
|December 11, 2019
PubMed
Summary
This summary is machine-generated.

The Index of Sparseness (IS) method is the most effective for variable selection in regularized simultaneous component analysis (regularized SCA). This data integration technique is crucial for interdisciplinary research combining diverse datasets like GPS and travel diaries.

More Related Videos

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance
09:01

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance

Published on: May 7, 2014

10.5K
Basics of Multivariate Analysis in Neuroimaging Data
06:35

Basics of Multivariate Analysis in Neuroimaging Data

Published on: July 24, 2010

17.3K

Related Experiment Videos

Last Updated: Jan 2, 2026

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance
09:01

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance

Published on: May 7, 2014

10.5K
Basics of Multivariate Analysis in Neuroimaging Data
06:35

Basics of Multivariate Analysis in Neuroimaging Data

Published on: July 24, 2010

17.3K

Area of Science:

  • Data Science
  • Statistics
  • Interdisciplinary Research

Background:

  • Interdisciplinary research frequently integrates data from multiple sources for comprehensive analysis.
  • Techniques like regularized simultaneous component analysis (regularized SCA) are used for joint analysis of diverse datasets, such as GPS and travel diary data.
  • Effective variable selection is critical for regularized SCA to identify joint and unique sources of variation.

Purpose of the Study:

  • To compare the performance of six different variable selection methods for regularized SCA.
  • To identify the most effective variable selection method for analyzing integrated datasets in interdisciplinary studies.

Main Methods:

  • The study simulated data with varying noise and sparseness levels.
  • Six variable selection methods were evaluated: cross-validation (CV) with the "one-standard-error" rule, repeated double CV (rdCV), BIC, Bolasso with CV, stability selection, and Index of Sparseness (IS).
  • Performance was assessed based on the ability to select appropriate variables for regularized SCA.

Main Results:

  • The Index of Sparseness (IS) demonstrated superior performance compared to the other five methods.
  • IS proved to be a computationally efficient and effective variable selection technique.
  • The findings highlight the importance of method selection for successful data integration.

Conclusions:

  • The Index of Sparseness (IS) is recommended as the preferred variable selection method for regularized SCA.
  • This research contributes to improving data integration techniques for complex interdisciplinary projects.
  • Accurate variable selection enhances the reliability and interpretability of results from joint data analysis.