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Cdc7 kinase stimulates Aurora B kinase in M-phase

Sayuri Ito1, Hidemasa Goto2, Kinue Kuniyasu3

  • 1Department of Genome Medicine, Tokyo Metropolitan Institute of Medical Science, Tokyo, 156-8506, Japan.

Scientific Reports
|December 11, 2019
PubMed
Summary

The cell division cycle 7 (Cdc7) kinase activates Aurora B kinase, promoting M-phase progression and the spindle assembly checkpoint. Cdc7 inhibition reverses mitotic arrest, highlighting its role in cell cycle regulation.

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