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3D Printed Microfluidics.

Anna V Nielsen1, Michael J Beauchamp1, Gregory P Nordin2

  • 1Department of Chemistry and Biochemistry, Brigham Young University, Provo, Utah 84602, USA;

Annual Review of Analytical Chemistry (Palo Alto, Calif.)
|December 11, 2019
PubMed
Summary
This summary is machine-generated.

Three-dimensional (3D) printing offers a promising alternative to traditional microfabrication for creating microfluidic devices. This advanced technique overcomes limitations in 3D architecture and design flexibility, paving the way for efficient microfluidic fabrication.

Keywords:
PDMSPolyJetadditive manufacturingfused deposition modelingmicrodevice fabricationpolydimethylsiloxanestereolithography

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Area of Science:

  • Materials Science
  • Engineering
  • Biotechnology

Background:

  • Traditional microfabrication methods struggle with 3D structures, design changes, and scaling up production.
  • Existing techniques are often costly and time-intensive for rapid prototyping.

Purpose of the Study:

  • To explore the potential of three-dimensional (3D) printing as an alternative microfluidic fabrication method.
  • To address the limitations of conventional microfabrication techniques.

Main Methods:

  • Review of emerging 3D printing technologies for microfluidic applications.
  • Focus on stereolithography as a leading approach for microfluidic structure creation.

Main Results:

  • 3D printing enables the creation of complex 3D microfluidic architectures.
  • Stereolithography shows significant promise for routine microfluidic fabrication.
  • While currently at the millifluidic scale, microfluidic applications are emerging.

Conclusions:

  • 3D printing is a rapidly developing field for microfluidics, analogous to early polydimethylsiloxane (PDMS) technology.
  • Advancements in hardware, software, materials, and applications are crucial for widespread adoption.
  • 3D printing is poised to become the primary method for microfluidic fabrication in the future.