Related Experiment Video
Updated: Jan 2, 2026

Protocol for Repetitive Transcranial Magnetic Stimulation with Symptom Provocation to Treat Obsessive-compulsive Disorder
Published on: November 25, 2025
Treatments for primary delusional infestation
Iyas Assalman1, Alia Ahmed2, Randa Alhajjar3
1East London NHS Foundation Trust, London, UK.
No studies were found to evaluate treatments for primary delusional infestation (DI). More research is needed to determine effective pharmacological and non-pharmacological options for this psychiatric disorder.
Area of Science:
- Psychiatry
- Dermatology
- Clinical Trials
Background:
- Primary delusional infestation (DI) is a psychiatric disorder with delusions and tactile sensations.
- Its pathophysiology remains unclear, and treatment options are diverse.
- DI presents a significant disease burden, frequently diagnosed by dermatologists and psychiatrists.
Purpose of the Study:
- To assess the efficacy of various treatments for primary delusional infestation (DI).
Main Methods:
- Searched trial registries for randomized controlled trials (RCTs) up to March 2019.
- Included RCTs focusing on adult primary DI treatment.
- Two reviewers independently screened studies.
Main Results:
- No eligible studies were identified for inclusion in the review.
- There is a lack of randomized controlled trials comparing treatments for primary DI.
Conclusions:
- No evidence exists from RCTs to support or refute treatments for primary delusional infestation.
- Conclusions on the effectiveness of pharmacological or non-pharmacological interventions cannot be drawn.
- Urgent need for robust randomized trials in the treatment of primary DI.
Related Concept Videos
Positive Symptoms Schizophrenia: Hallucinations and Delusions
Hallucinations
Hallucinations in...
Psychosis: Goals of Pharmacotherapy
Psychosis and Antipsychotic Drugs: Overview
Treatment Strategies for Psychological Disorders
Psychological therapies focus on modifying emotions, thoughts, and behaviors through talking, interpreting, listening, rewarding, challenging, and modeling. Clinical psychologists, counselors, and social workers commonly practice psychotherapy. Clinical...
Positive Symptoms of Schizophrenia: Hallucinations and Delusions
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes...
Personality Disorders: Paranoid and Schizoid
Paranoid Personality Disorder
Paranoid personality disorder is...

