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Scanning Electron Microscopic Evaluation of Surface Defects of Remover Retreatment File After Single and Multiple Uses
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Relapses after using Carnoy's solution in treating aggressive benign odontogenic lesions.

Danielle C Costa1, Larissa de O Silveira1, Salomão I Queiroz1

  • 1Department of Dentistry, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.

Minerva Stomatologica
|December 12, 2019
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Summary

This study found that the enucleation protocol with peripheral ostectomy and Carnoy's solution has a 23.3% relapse rate, primarily in odontogenic keratocysts. Preserving adjacent teeth increased relapse risk and time.

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Area of Science:

  • Oral and Maxillofacial Surgery
  • Oncology
  • Pathology

Background:

  • Benign aggressive odontogenic lesions require effective treatment.
  • Chemical curettage using Carnoy's solution is a popular treatment modality.
  • Assessing treatment outcomes is crucial for clinical decision-making.

Purpose of the Study:

  • To evaluate the relapse rate following enucleation, peripheral ostectomy, and Carnoy's solution.
  • To identify prognostic factors associated with relapse in odontogenic lesions.
  • To compare this protocol with alternative treatments.

Main Methods:

  • Retrospective sectional study of 30 patients treated between 2008 and 2018.
  • Data collected from medical records, including clinical and radiographic analysis.
  • Statistical analysis using Mann-Whitney, Fisher's Exact, and Chi-squared tests, Kaplan-Meier, and Log-rank tests (P<0.05).

Main Results:

  • The study included 22 odontogenic keratocysts, 3 odontogenic myxomas, and 5 ameloblastomas.
  • A 23.3% relapse rate was observed, exclusively in odontogenic keratocysts, with relapse occurring 12-34 months post-treatment.
  • Patients retaining adjacent teeth had an earlier relapse and a 5.5 times higher risk compared to those with tooth extraction.

Conclusions:

  • The enucleation, peripheral ostectomy, and Carnoy's solution protocol demonstrates an acceptable relapse rate.
  • This protocol can be a viable alternative to more extensive surgical resection.
  • Preserving adjacent teeth may increase the risk of relapse for odontogenic keratocysts.