Cefoxitin in treatment of obstetric and gynecologic infections

Cefoxitin was found to be an effective and safe agent for the treatment of infections of the female genital tract that were associated with a variety of aerobic and anaerobic bacteria, including Streptococcus, Escherichia coli, and Bacteroides species. The overall clinical response was 91%. The major cause of failure was the presence of an abscess requiring surgical drainage. Both the intravenous and the intramuscular routes of administration for cefoxitin were tolerated well or moderately well by most patients.