An abnormal finding in the third trimester.

Area of Science:

• Neonatal Medicine
• Maternal-Fetal Medicine
• Pediatric Neurology

Background:

• A healthy woman experienced antepartum hemorrhage in late gestation.
• Routine antenatal screening showed normal results until an abnormal ultrasound (USS) was performed.

Purpose of the Study:

• To report a case of a neonate with neurological deficits and skeletal abnormalities following antepartum hemorrhage.
• To highlight the importance of thorough neonatal examination and prompt investigation of abnormal findings.

Main Methods:

• Case report of a singleton pregnancy complicated by antepartum hemorrhage.
• Emergency Cesarean section performed due to abnormal ultrasound findings.
• Detailed neonatal examination and biochemical investigations.

Main Results:

• The infant exhibited global hypotonia, weak suck, absent Moro reflex, widened sagittal sutures, and a large posterior fontanelle.
• Abnormal blood tests were noted (detailed in Table 1).

Conclusions:

• The clinical presentation suggests a possible underlying genetic or metabolic disorder requiring further investigation.
• Early identification of neonatal signs and symptoms is crucial for timely diagnosis and management.