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Porcine Parvovirus
André Felipe Streck1, Uwe Truyen2
1Veterinary Diagnostic Laboratory, Faculty of Veterinary Medicine, University of Caxias do Sul, Caxias do Sul, Brazil.
Current Issues in Molecular Biology
|December 12, 2019
Summary
Porcine parvovirus (PPV) causes significant reproductive issues in pigs, including stillbirth and infertility. This review covers PPV biology, disease, and newer related parvoviruses found in swine.
Area of Science:
- Veterinary Virology
- Swine Disease Research
- Animal Reproduction
Background:
- Porcine parvovirus (PPV) is a primary cause of SMEDI (stillbirth, mummification, embryonic death, infertility) syndrome in pigs.
- Understanding PPV's biology, pathogenesis, and strain variation is crucial for swine health management.
Purpose of the Study:
- To review the biology, structure, pathogenesis, and diagnosis of Porcine parvovirus (PPV).
- To discuss the disease induced by PPV and its prevention, focusing on vaccination strategies.
- To explore recently identified "new" porcine parvoviruses (PPV2-7) and their potential clinical significance.
Main Methods:
- Literature review of existing studies on Porcine parvovirus.
- Analysis of data on PPV biology, pathogenesis, and strain diversity.
- Compilation of information on diagnostic methods and vaccination efficacy.
Main Results:
- PPV is a well-established cause of reproductive failure in swine.
- Various PPV strains exhibit different pathogenic potentials.
- Newer parvoviruses (PPV2-7) have been identified in global swine populations, with their disease association under investigation.
Conclusions:
- Effective control of PPV-induced reproductive disorders relies on understanding its biology and implementing preventive measures like vaccination.
- Further research is needed to elucidate the role of novel porcine parvoviruses (PPV2-7) in swine health and disease.
