Related Experiment Video
Updated: Jan 2, 2026
Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics
Published on: November 29, 2024
Statistical reporting of metabolomics data: experience from a high-throughput NMR platform and epidemiological
Stefan Mutter1,2,3,4, Carrie Worden5, Kara Paxton5
1Computational Systems Biology Program, Precision Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, Australia. stefan.mutter@helsinki.fi.
Introduction:
Meta-analysis is the cornerstone of robust biomedical evidence.
Objectives:
We investigated whether statistical reporting practices facilitate metabolomics meta-analyses.
Methods:
A literature review of 44 studies that used a comparable platform.
Results:
Non-numeric formats were used in 31 studies. In half of the studies, less than a third of all measures were reported. Unadjusted P-values were missing from 12 studies and exact P-values from 9 studies.
Conclusion:
Reporting practices can be improved. We recommend (i) publishing all results as numbers, (ii) reporting effect sizes of all measured metabolites and (iii) always reporting unadjusted exact P-values.
