Related Experiment Video
Updated: Jan 2, 2026
07:44
A Porcine Model of Acute Autologous Pulmonary Embolism
Published on: September 6, 2024
725
Home treatment for pulmonary embolism
Summary
Home treatment for pulmonary embolism is safe and effective for selected patients. The Hestia criteria offer a practical method for identifying suitable candidates for early discharge and outpatient care.
Area of Science:
- Medicine
- Cardiology
- Pulmonology
Background:
- Early discharge and home treatment for pulmonary embolism (PE) may reduce hospital complications and costs.
- Investigating the safety and efficacy of home treatment compared to hospital treatment is crucial.
- Identifying optimal patient selection criteria for home-based PE care is needed.
Purpose of the Study:
- To determine if home treatment for pulmonary embolism is as safe and effective as inpatient hospital treatment.
- To identify the best criteria for selecting patients suitable for home treatment of pulmonary embolism.
Main Methods:
- Conducted a systematic search of Embase, MEDLINE, and the Cochrane Library.
- Included clinical trials comparing hospital treatment versus home treatment for acute, objectively verified pulmonary embolism.
- Evaluated outcomes for patients receiving different treatment settings.
Main Results:
- Home treatment is as safe and effective as hospital treatment for a selected group of acute, symptomatic pulmonary embolism patients.
- The Pulmonary Embolism Severity Index (PESI) and Hestia criteria demonstrate strong clinical utility for patient selection.
- These criteria aid in identifying patients appropriate for home-based management.
Conclusions:
- Home treatment is a viable and safe option for carefully selected pulmonary embolism patients.
- The Hestia criteria provide a pragmatic and effective tool for selecting patients for home treatment.
- Application of Hestia criteria can facilitate early discharge and reduce healthcare resource utilization.
Related Concept Videos
01:27Pulmonary Embolism III: Nursing Management
287
A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
287
01:29Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
248
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
248
01:29Pulmonary Embolism I: Introduction
437
Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
437
01:29Venous Thrombosis III: Interprofessional Care
240
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
240
01:30Venous Thrombosis IV: Nursing Management
165
Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
165
01:23Treatment for Pulmonary Arterial Hypertension: Prostacyclin Receptor Agonists
404
Prostacyclin receptor agonists are a class of therapeutic agents integral to managing pulmonary arterial hypertension (PAH). These drugs operate by mimicking the action of prostaglandin I2, or PGI2, a naturally occurring compound in the body.
These agonists bind to the IPR receptor situated on the plasma membrane of the pulmonary artery smooth muscle cells. This binding triggers a cascade of reactions known as the GS-AC-cAMP-PKA pathway. This pathway results in the relaxation of smooth muscle...
These agonists bind to the IPR receptor situated on the plasma membrane of the pulmonary artery smooth muscle cells. This binding triggers a cascade of reactions known as the GS-AC-cAMP-PKA pathway. This pathway results in the relaxation of smooth muscle...
404