Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Adipose tissue signaling in aldosterone-producing adenomas: paracrine and endocrine effects.

European journal of endocrinology·2025
Same author

Release mechanisms of PLGA microparticles prepared using a microfluidics device or a beaker.

International journal of pharmaceutics: X·2025
Same author

Laparoscopic vs. Robotic transabdominal adrenalectomy- propensity matched analysis and learning curve.

Langenbeck's archives of surgery·2025
Same author

Chronic postoperative inguinal pain (CPIP) after pediatric inguinal hernia repair-a retrospective analysis.

Hernia : the journal of hernias and abdominal wall surgery·2025
Same author

EVA implants for controlled drug delivery to the inner ear.

International journal of pharmaceutics: X·2024
Same author

Chronic postsurgical pain (CPSP): an underestimated problem after incisional hernia treatment.

Hernia : the journal of hernias and abdominal wall surgery·2024

Related Experiment Video

Updated: Jan 2, 2026

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models
10:19

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models

Published on: August 9, 2012

19.8K

Bladder Augmentation Using Lyoplant®: First Experimental Results in Rats.

F Winde1, K Backhaus1, J A Zeitler2

  • 11Pediatric Surgery-, Pediatric Trauma - and Pediatric Urology Unit, Department of General-, Visceral-, Transplant-, Vascular- and Pediatric Surgery, University Hospital Wuerzburg, Würzburg, Germany.

Tissue Engineering and Regenerative Medicine
|December 12, 2019
PubMed
Summary

Lyoplant collagen mesh shows promise for bladder augmentation in rats, offering a potential alternative to intestinal tissue grafts. This biocompatible material demonstrated successful integration and regeneration, minimizing complications associated with current methods.

Keywords:
Biocompatible collagen meshBladder regeneration/augmentationRat model

More Related Videos

Minimally Invasive Establishment of Murine Orthotopic Bladder Xenografts
08:15

Minimally Invasive Establishment of Murine Orthotopic Bladder Xenografts

Published on: February 11, 2014

16.3K
Surgical Model for Single-Staged Tissue-Engineered Urothelial Tubes in Minipigs
04:05

Surgical Model for Single-Staged Tissue-Engineered Urothelial Tubes in Minipigs

Published on: July 5, 2024

616

Related Experiment Videos

Last Updated: Jan 2, 2026

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models
10:19

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models

Published on: August 9, 2012

19.8K
Minimally Invasive Establishment of Murine Orthotopic Bladder Xenografts
08:15

Minimally Invasive Establishment of Murine Orthotopic Bladder Xenografts

Published on: February 11, 2014

16.3K
Surgical Model for Single-Staged Tissue-Engineered Urothelial Tubes in Minipigs
04:05

Surgical Model for Single-Staged Tissue-Engineered Urothelial Tubes in Minipigs

Published on: July 5, 2024

616

Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Urology

Background:

  • Congenital bladder defects pose significant challenges in pediatric surgery, often leading to renal dysfunction and failure.
  • Current bladder augmentation using intestinal tissue has limitations, including infections and stone formation.
  • Existing substitutes for bladder augmentation have not yet proven successful.

Purpose of the Study:

  • To evaluate the biocompatibility and efficacy of Lyoplant, a collagen mesh, as a substitute for bladder augmentation.
  • To assess Lyoplant's potential in an experimental rat model for bladder defects.

Main Methods:

  • A bladder defect rat model was used, implanting Lyoplant mesh for augmentation.
  • The study involved a Lyoplant group (n=12) and a sham group (n=4).
  • Histological and immunohistochemical analyses were performed after 6 weeks.

Main Results:

  • Rats in the Lyoplant group showed normal physiological growth and behavior, similar to the sham group.
  • No significant complications like wound infections or herniation were observed.
  • Histological analysis confirmed adequate implant incorporation, significant cell infiltration, and neovascularization within 5 weeks.

Conclusions:

  • Lyoplant collagen mesh demonstrates potential as a viable material for experimental bladder augmentation and regeneration.
  • The biocompatible mesh facilitated tissue integration and vascularization, suggesting a promising alternative to intestinal tissue grafts.