Related Experiment Video
Updated: Jan 2, 2026
09:03
The Perinatal Asphyxiated Lamb Model: A Model for Newborn Resuscitation
Published on: August 15, 2018
11.2K
Placental Transfusion for Asphyxiated Infants
Anup C Katheria1, Wade D Rich1, Sunita Bava2
1Sharp Mary Birch Hospital for Women & Newborns, San Diego, CA, United States.
Frontiers in Pediatrics
|December 12, 2019
Summary
Immediate umbilical cord clamping is recommended for non-vigorous infants needing resuscitation. However, delayed cord clamping or umbilical cord milking may offer neuroprotection and aid cardiovascular transition, despite limited evidence.
Area of Science:
- Neonatal Resuscitation
- Perinatal Medicine
- Pediatric Cardiology
Background:
- Current guidelines recommend immediate umbilical cord clamping for non-vigorous infants requiring resuscitation.
- There is limited evidence supporting delayed cord clamping (DCC) or umbilical cord milking (UCM) in this population.
- These practices may influence neonatal outcomes and cardiovascular adaptation.
Purpose of the Study:
- To evaluate the potential benefits of DCC and UCM for non-vigorous infants.
- To explore the neuroprotective and cardiovascular transition effects of alternative cord management strategies.
- To address the evidence gap in managing the umbilical cord for compromised newborns.
Main Methods:
- Review of existing literature on neonatal resuscitation and cord management.
- Analysis of physiological responses to DCC and UCM in non-vigorous neonates.
- Comparison of outcomes between immediate clamping and alternative methods.
Main Results:
- Delayed cord clamping and umbilical cord milking may offer benefits for non-vigorous infants.
- These methods show potential for neuroprotection and improved cardiovascular transition.
- Further research is needed to establish definitive efficacy and safety.
Conclusions:
- Delayed cord clamping and umbilical cord milking warrant further investigation for non-vigorous infants.
- These techniques may represent a paradigm shift in neonatal resuscitation protocols.
- Evidence supporting these alternative cord management strategies is emerging.
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