Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Potential Due to a Polarized Object01:29

Potential Due to a Polarized Object

687
A neutral atom consists of a positively charged nucleus surrounded by a negatively charged electron cloud. When placed in an external electric field, the external electric force pulls the electrons and nucleus apart, opposite to the intrinsic attraction between the nucleus and the electrons. The opposing forces balance each other with a slight shift between the center of masses of the nucleus and the electron cloud, resulting in a polarized atom. On the other hand, a few molecules, like water,...
687
Mechanically-gated Ion Channels01:12

Mechanically-gated Ion Channels

7.5K
Mechanically-gated ion channels are proteins found in eukaryotic and prokaryotic cell membranes that open in response to mechanical stress. Tension, compression, swelling, and shear stress can alter the conformation of the protein, opening a transmembrane channel that allows the passage of ions for signal transmission. In eukaryotes, mechanically-gated channels are distributed in several regions like the neurons, lungs, skin, bladder, and heart, where they play critical roles in numerous...
7.5K
Equipotential Surfaces and Conductors01:16

Equipotential Surfaces and Conductors

4.3K
For a conductor in which all charges are at rest, the conductor's surface is equipotential. The electric field is always perpendicular to equipotential surfaces. Therefore, in a conductor with static charges, the electric field just outside the conductor is always perpendicular to the conductor's surface. Any tangential component of the electric field will cause charges to move inside the conductor, which will violate the electrostatic nature of the system. In an electrostatic...
4.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluation of metal-oxide semiconductors for the photocatalytic degradation of chloroquine phosphate in real-world water matrices.

Scientific reports·2026
Same author

Electrospun Polyurethane-Based Nanofibrous Membranes Functionalized with UiO-66-NH<sub>2</sub> for Water Remediation.

Polymers·2026
Same author

Piezoelectric Surface Charge and Dynamic Stimulation Synergize to Promote Cardiac Myoblast Alignment and Maturation.

Advanced healthcare materials·2026
Same author

Resolving Complex Multiscale Structure of Magneto- and Electroactive Polymer Composites With an Ionic Liquid.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Zirconium(IV)-Succimer Metal-Organic Framework Functionalized PVDF-HFP Membranes for Heavy-Metals Capture.

Chemistry (Weinheim an der Bergstrasse, Germany)·2026
Same author

Processing-Structure-Property Relationships in Poly(vinylidene fluoride) Composites Containing Metal Organic Frameworks and Ionic Liquids: A Roadmap for Application-Driven Design.

ACS applied materials & interfaces·2026

Related Experiment Video

Updated: Jan 2, 2026

Investigating the Potential of Singly Curved Thin Piezoelectric Transducers for Energy Harvesting and Structural Health Monitoring
07:02

Investigating the Potential of Singly Curved Thin Piezoelectric Transducers for Energy Harvesting and Structural Health Monitoring

Published on: November 14, 2025

616

Surface Charge-Mediated Cell-Surface Interaction on Piezoelectric Materials.

Sylvie Ribeiro1, Christina Puckert2, Clarisse Ribeiro1

  • 1Centro/Departamento de Física , Universidade do Minho , 4710-057 Braga , Portugal.

ACS Applied Materials & Interfaces
|December 12, 2019
PubMed
Summary
This summary is machine-generated.

Surface charge on piezoelectric poly(vinylidene fluoride) (PVDF) materials significantly impacts skeletal muscle cell adhesion. Negatively charged PVDF enhances cell attachment, offering potential for improved tissue engineering strategies.

Keywords:
cell adhesioncell−material interactionselectrostatic interactionsmuscle cellspiezoelectric materialssingle-cell force spectroscopy

More Related Videos

Characterization of Full Set Material Constants and Their Temperature Dependence for Piezoelectric Materials Using Resonant Ultrasound Spectroscopy
07:44

Characterization of Full Set Material Constants and Their Temperature Dependence for Piezoelectric Materials Using Resonant Ultrasound Spectroscopy

Published on: April 27, 2016

10.0K
Fabrication and Characterization of Thickness Mode Piezoelectric Devices for Atomization and Acoustofluidics
10:39

Fabrication and Characterization of Thickness Mode Piezoelectric Devices for Atomization and Acoustofluidics

Published on: August 5, 2020

7.3K

Related Experiment Videos

Last Updated: Jan 2, 2026

Investigating the Potential of Singly Curved Thin Piezoelectric Transducers for Energy Harvesting and Structural Health Monitoring
07:02

Investigating the Potential of Singly Curved Thin Piezoelectric Transducers for Energy Harvesting and Structural Health Monitoring

Published on: November 14, 2025

616
Characterization of Full Set Material Constants and Their Temperature Dependence for Piezoelectric Materials Using Resonant Ultrasound Spectroscopy
07:44

Characterization of Full Set Material Constants and Their Temperature Dependence for Piezoelectric Materials Using Resonant Ultrasound Spectroscopy

Published on: April 27, 2016

10.0K
Fabrication and Characterization of Thickness Mode Piezoelectric Devices for Atomization and Acoustofluidics
10:39

Fabrication and Characterization of Thickness Mode Piezoelectric Devices for Atomization and Acoustofluidics

Published on: August 5, 2020

7.3K

Area of Science:

  • Biomaterials Science
  • Tissue Engineering
  • Cell Biology

Background:

  • Cell-material interactions are crucial for scaffold-based tissue engineering.
  • Severe muscle injuries leading to cell loss limit current cell therapies.
  • Electroactive and piezoelectric materials offer promising electroactive microenvironments for tissue development.

Purpose of the Study:

  • To investigate the influence of surface charge on piezoelectric poly(vinylidene fluoride) (PVDF) on C2C12 myoblast cell adhesion.
  • To analyze cell-material interactions using atomic force microscopy (AFM) and immunofluorescence staining.

Main Methods:

  • Culturing C2C12 myoblast cells on PVDF samples with varying surface charges.
  • Immunofluorescence staining to observe cytoskeletal organization.
  • Single-cell force spectroscopy (SCFS) using AFM to quantify cell-material interactions.

Main Results:

  • C2C12 cells exhibited a more elongated morphology on PVDF samples with a net surface charge, irrespective of charge polarity.
  • Cell deadhesion forces were significantly higher on negatively charged PVDF (8.92 ± 0.45 nN) compared to nonpoled substrates (4.06 ± 0.20 nN).

Conclusions:

  • Surface charge polarization of PVDF is a critical parameter influencing C2C12 cell adhesion.
  • Enhanced cell adhesion on charged PVDF substrates can impact cell proliferation and differentiation, advancing skeletal muscle tissue engineering.