Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Recruitment strategies for lung cancer screening; a randomised trial in the 4-IN-THE-LUNG-RUN study.

Lung cancer (Amsterdam, Netherlands)·2026
Same author

Evolving attitudes towards cancer screening: a 2024 update of UK population views.

British journal of cancer·2026
Same author

Expanded detection of early fibrotic phenotypes using lobar traction bronchiolectasis in lung cancer screening.

American journal of respiratory and critical care medicine·2026
Same author

How to Translate Quality Standards Into Good Lung Cancer Screening Programmes: The UK Experience.

British journal of hospital medicine (London, England : 2005)·2026
Same author

AI-based chest X-ray prioritization in the lung cancer diagnostic pathway: the LungIMPACT randomized controlled trial.

Nature medicine·2026
Same author

Implementation of the NHS England Lung Cancer Screening Programme over 5 years.

Nature medicine·2026

Related Experiment Video

Updated: Jan 2, 2026

Lung Tumor Cell Recruitment Assay
04:28

Lung Tumor Cell Recruitment Assay

Published on: February 26, 2019

5.8K

Lung Screen Uptake Trial (LSUT): Randomized Controlled Clinical Trial Testing Targeted Invitation Materials.

Samantha L Quaife1, Mamta Ruparel2, Jennifer L Dickson2

  • 1Research Department of Behavioural Science and Health and.

American Journal of Respiratory and Critical Care Medicine
|December 12, 2019
PubMed
Summary
This summary is machine-generated.

A targeted lung cancer screening invitation strategy did not increase uptake compared to standard care. However, the Lung Health Check approach showed higher attendance than previous studies, especially for lower socioeconomic groups.

Keywords:
behavioral sciencesearly detection of cancerlung neoplasmssocioeconomic factors

More Related Videos

E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
06:28

E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy

Published on: August 1, 2019

8.7K
Visualizing Field Data Collection Procedures of Exposure and Biomarker Assessments for the Household Air Pollution Intervention Network Trial in India
09:33

Visualizing Field Data Collection Procedures of Exposure and Biomarker Assessments for the Household Air Pollution Intervention Network Trial in India

Published on: December 23, 2022

2.6K

Related Experiment Videos

Last Updated: Jan 2, 2026

Lung Tumor Cell Recruitment Assay
04:28

Lung Tumor Cell Recruitment Assay

Published on: February 26, 2019

5.8K
E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
06:28

E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy

Published on: August 1, 2019

8.7K
Visualizing Field Data Collection Procedures of Exposure and Biomarker Assessments for the Household Air Pollution Intervention Network Trial in India
09:33

Visualizing Field Data Collection Procedures of Exposure and Biomarker Assessments for the Household Air Pollution Intervention Network Trial in India

Published on: December 23, 2022

2.6K

Area of Science:

  • Public Health
  • Preventive Medicine
  • Health Services Research

Background:

  • Low-dose computed tomography (LDCT) lung cancer screening uptake is suboptimal, particularly among current smokers from lower socioeconomic backgrounds, impacting program effectiveness and equity.
  • Targeted strategies are needed to improve participation in lung cancer screening programs.
  • Hospital-based Lung Health Checks offer LDCT screening but require effective outreach to maximize attendance.

Purpose of the Study:

  • To evaluate the impact of a targeted, low-burden, stepped invitation strategy on the uptake of hospital-based Lung Health Check appointments offering LDCT screening.
  • To compare the effectiveness of an intervention leaflet addressing psychological barriers against a control group.
  • To identify factors influencing screening appointment attendance.

Main Methods:

  • A two-arm, blinded, randomized controlled trial involving 2,012 participants aged 60-75 who were current or recent smokers without LDCT contraindications.
  • Participants received stepped invitations (preinvitation, invitation, reminder) from primary care practices.
  • The intervention group received an additional leaflet designed to address psychological barriers and provide low-burden information, mimicking a vehicle test concept.

Main Results:

  • Overall uptake was 52.6%, with no statistically significant difference between the intervention (52.3%) and control (52.9%) groups.
  • Current smokers were less likely to attend appointments than former smokers (adjusted OR, 0.70).
  • Socioeconomic deprivation was associated with lower uptake in the control group only (P < 0.01).

Conclusions:

  • The tested intervention strategy did not significantly improve LDCT lung cancer screening uptake.
  • The Lung Health Check approach, common to both arms, resulted in higher uptake than previously reported, especially among lower socioeconomic position smokers.
  • The findings suggest that the Lung Health Check model itself may represent a successful baseline strategy for lung cancer screening outreach.