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Updated: Jan 2, 2026

A Simplified Technique for Producing an Ischemic Wound Model
Published on: May 2, 2012
Successful treatment of a diabetic foot ulcer with exposed bone using Trigona honey: a case study
Adam Astrada1,2, Gojiro Nakagami1,3, Suriadi Jais4,5
1Department of Gerontological Nursing/Wound Care Management, Graduate School of Medicine, the University of Tokyo, Japan.
Abstract:
Many studies have shown that honey might improve wound healing. However, its efficacy for large wounds which may be followed by a systemic effect remains unclear. The effectiveness of honey-based dressings in treating large diabetic foot ulcers (DFU) is still unknown. This study presents the case of a 38-year-old female patient presenting with an extensive infected DFU with exposed bone. The DFU was treated with propolis-enriched Trigona honey, used as a single treatment, in a home visit setting. After two months' follow-up, the wound exhibited complete re-epithelialisation despite the patient's initial poor condition.
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