Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Role of Hippocampus in Memory01:19

Role of Hippocampus in Memory

1.3K
The hippocampus, a critical brain structure, plays an essential role in memory processing, particularly in the formation and retrieval of memory. This small, seahorse-shaped region is located within the medial temporal lobe, with one hippocampus in each brain hemisphere. Experimental studies involving lesions in the hippocampi of rats have demonstrated significant impairments in tasks such as object recognition and maze navigation, indicating the hippocampus involvement in both recognition and...
1.3K
Encoding01:19

Encoding

695
Information enters the brain through encoding, which is the input of information into the memory system. Once sensory information is received from the environment, the brain labels or codes it. The information is then organized with similar information and connected to existing concepts. Encoding occurs through automatic processing and effortful processing.
Automatic processing involves the encoding of details like time, space, frequency, and the meaning of words, usually done without conscious...
695
Storage01:23

Storage

303
A schema is a mental framework that helps individuals organize and interpret information. Schemata, formed from previous experiences, influence how we process new information: how we encode it, the inferences we make, and how we retrieve it. For instance, a schema for what a typical classroom looks like might include desks, a teacher's desk, a whiteboard, and students in such an environment. This expectation helps us quickly understand and navigate new classrooms without needing to analyze...
303
Functional Brain Systems: Limbic System01:15

Functional Brain Systems: Limbic System

6.1K
The limbic system, often called the "emotional brain," is a complex set of structures located deep within the brain. The intricate network of the limbic system supports a wide range of psychological functions, from emotional regulation to memory formation and sensory processing. This functional brain region encompasses specific parts of the diencephalon and the cerebrum, integrating the higher mental functions of the cerebral cortex with the primitive emotional responses of the deep brain...
6.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Neural Signatures of Recollection Are Sensitive to Memory Quality and Specific Event Features.

Journal of cognitive neuroscience·2025
Same author

Neural signatures of recollection are sensitive to memory quality and specific event features.

bioRxiv : the preprint server for biology·2025
Same author

Eye tracking evidence for the reinstatement of emotionally negative and neutral memories.

PloS one·2024
Same author

Intrinsic functional connectivity among memory networks does not predict individual differences in narrative recall.

bioRxiv : the preprint server for biology·2024
Same author

Hippocampal Functions Modulate Transfer-Appropriate Cortical Representations Supporting Subsequent Memory.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2023
Same author

Integrating Region- and Network-level Contributions to Episodic Recollection Using Multilevel Structural Equation Modeling.

Journal of cognitive neuroscience·2022

Related Experiment Video

Updated: Jan 2, 2026

Investigating Long-term Synaptic Plasticity in Interlamellar Hippocampus CA1 by Electrophysiological Field Recording
14:27

Investigating Long-term Synaptic Plasticity in Interlamellar Hippocampus CA1 by Electrophysiological Field Recording

Published on: August 11, 2019

13.2K

Progression from Feature-Specific Brain Activity to Hippocampal Binding during Episodic Encoding.

Rose A Cooper1, Maureen Ritchey2

  • 1Department of Psychology, Boston College, Chestnut Hill, Massachusetts 02467 rose.cooper@bc.edu.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
|December 13, 2019
PubMed
Summary
This summary is machine-generated.

The brain encodes event details using distinct early frontal and sensory processes, then integrates them in the hippocampus later. This reveals how we form coherent memories from multiple features over time.

Keywords:
encodingepisodic memoryhippocampus

More Related Videos

Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease
09:38

Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease

Published on: November 14, 2017

15.5K
Investigations on Alterations of Hippocampal Circuit Function Following Mild Traumatic Brain Injury
10:59

Investigations on Alterations of Hippocampal Circuit Function Following Mild Traumatic Brain Injury

Published on: November 19, 2012

15.7K

Related Experiment Videos

Last Updated: Jan 2, 2026

Investigating Long-term Synaptic Plasticity in Interlamellar Hippocampus CA1 by Electrophysiological Field Recording
14:27

Investigating Long-term Synaptic Plasticity in Interlamellar Hippocampus CA1 by Electrophysiological Field Recording

Published on: August 11, 2019

13.2K
Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease
09:38

Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease

Published on: November 14, 2017

15.5K
Investigations on Alterations of Hippocampal Circuit Function Following Mild Traumatic Brain Injury
10:59

Investigations on Alterations of Hippocampal Circuit Function Following Mild Traumatic Brain Injury

Published on: November 19, 2012

15.7K

Area of Science:

  • Cognitive Neuroscience
  • Neuroimaging
  • Memory Research

Background:

  • Episodic memory relies on integrating perceptual details within a spatial-temporal context.
  • Understanding how the brain binds diverse features into coherent event representations is crucial for socio-cognitive abilities.

Purpose of the Study:

  • To investigate how the brain simultaneously encodes and binds multiple, distinct features of an event over time.
  • To examine the temporal dynamics of neural signatures during episodic encoding and their relation to memory recall.

Main Methods:

  • Functional magnetic resonance imaging (fMRI) was used to analyze brain activity in 27 human subjects.
  • Subjects learned objects associated with color, scene location, and emotional sound.
  • Brain activity was modeled in relation to memory for upcoming or just-viewed information.

Main Results:

  • Early encoding involved left inferior frontal and visuo-perceptual regions, tracking recalled details and distinguishing features.
  • Later encoding showed a shift to the left hippocampus, crucial for binding item features (color, sound) with spatial information.
  • A dissociation was observed between early feature-specific encoding and later hippocampal integration.

Conclusions:

  • Episodic encoding involves distinct temporal stages: early simultaneous feature processing and later integration.
  • The hippocampus plays a key role in binding diverse sensory and spatial information into a unified episodic experience.
  • Considering the temporal dynamics of encoding is vital for understanding multimodal event representations.