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Published on: December 6, 2016
Obstructive Sleep Apnea in School-Aged Children Presented with Nocturnal Enuresis
Hanaa Shafiek1,2, Melania Evangelisti3, Nashwa Hassan Abd-Elwahab4
1Department of Chest Diseases, Faculty of Medicine, Alexandria University, El-Khartoom Square, Alexandria, 21526, Egypt. whitecoat_med@yahoo.com.
Insights
Obstructive sleep apnea (OSA) is common in children with nocturnal enuresis (NE), particularly those who are obese. Nasal obstruction and specific facial features are key risk factors for OSA in this population.
Area of Science:
- Pediatric Sleep Medicine
- Childhood Respiratory Disorders
- Clinical Pediatrics
Background:
- Nocturnal enuresis (NE) is a common condition in school-aged children.
- Obstructive sleep apnea (OSA) is increasingly recognized as a potential underlying cause or contributing factor to NE.
- Identifying risk factors for OSA in children with NE is crucial for timely diagnosis and intervention.
Purpose of the Study:
- To determine the prevalence of obstructive sleep apnea (OSA) in school-aged children presenting with nocturnal enuresis (NE).
- To identify potential risk factors associated with OSA in this pediatric population.
Main Methods:
- Sixty-six children aged 5-16 years with NE were enrolled, excluding those with specific comorbidities.
- Clinical examinations, Sleep Clinical Record (SCR) scoring, and full-night polysomnograms (PSG) were performed.
- OSA was defined as an apnea/hypopnea index (AHI) of ≥2 episodes/hour.
Main Results:
- Of 54 children who underwent PSG, 68.5% were diagnosed with OSA (median AHI 6.1 episodes/h).
- Obesity was significantly associated with higher AHI (p=0.023).
- Nasal obstruction, adenoid facies, and high-arched palate were identified as significant risk factors for OSA (p<0.05).
Conclusions:
- Nocturnal enuresis (NE) is frequently associated with obstructive sleep apnea (OSA) in children, especially those who are obese.
- Clinical indicators such as nasal obstruction, abnormal facial phenotype, and high-arched palate are important risk factors for OSA in children with NE.
- These findings highlight the importance of screening for OSA in children with NE.
Objectives:
We aimed to detect obstructive sleep apnea (OSA) among school-age children presented with nocturnal enuresis (NE) and to identify the possible risk factors for OSA in them.
Methods:
Sixty-six children aged > 5-16 years presented with NE were enrolled in the study. Children with urinary tract anatomical abnormalities or infection, intellectual disabilities, genetic syndromes, psychological issues, and diabetes mellitus were excluded. They were clinically examined, scored using sleep clinical record score (SCR), and subjected for full-night polysomnogram (PSG). Children with obstructive apnea/hypopnea index (AHI) ≥ 2 episodes/hour (h) were considered as OSA.
Results:
Fifty-four children (81.8% of the recruited children) aged 8.3 ± 2.8 years agreed to undergo PSG as 68.5% had OSA with median obstructive AHI of 6.1 (3.7-13.2) episodes/h, median oxygen saturation of 97% and nadir of 88%. Thirty-three percent were obese with significantly higher AHI [7.0 (3.7-12.4) vs. 2.4 (1.3-6.1) episodes/h; p = 0.023]. SCR score correlated significantly with AHI (r2 = 0.462, p = 0.001) with 91% sensitivity in detecting OSA ≥ 5 episodes/h. Nasal obstruction, adenoid/adult facial phenotype, and arched palate were associated with OSA (p < 0.05).
Conclusion:
NE is commonly associated with OSA especially in obese children. Nasal obstruction, abnormal facial phenotype, and high-arched palate were common risk factors.
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