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In Vivo Mouse Model of Spinal Implant Infection
Published on: June 23, 2020
[Post-neurosurgical infections. Update and intersociety recommendations]
Javie Farina1, Ángel M Colque2, Marcelo Del Castillo3
1Hospital Italiano de la Plata, Argentina.
Abstract:
Infections associated with neurosurgical procedures are serious complications that contribute to the morbidity and mortality of neurocritical patients, as well as to the prolongation of the stay in the ICU and the hospital. The diagnosis is complex since there is no gold standard, so it is based on clinical suspicion, CSF physical-chemical examination, and microbial isolation. Treatment should be initiated early, guided by local epidemiology. The duration will depend on the causative microorganism, its sensitivity and the availability of antibiotic treatments that are effective at the site of infection. The implementation of preventive measures with proven efficacy minimizes the risk of infection. This SADI-SATI intersociety update reviews relevant data recently published on this area at the national at international level regarding epidemiology, diagnostic methodologies, therapeutic approaches, and prevention guidelines.
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