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Updated: Jan 2, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
An adaptive term proximity based rocchio's model for clinical decision support retrieval
Min Pan1,2, Yue Zhang3, Qiang Zhu3
1National Engineering Research Center for E-Learning, Central China Normal University, Wuhan, 430079, China.
This study introduces a new model for connecting electronic health records with biomedical literature, improving information retrieval for clinicians. The HAL-based Rocchio model (HRoc) enhances search precision and recall by considering term proximity.
Area of Science:
- Medical Informatics
- Information Retrieval
- Natural Language Processing
Background:
- Connecting electronic health records (EHR) with biomedical literature is crucial for clinical decision-making.
- Pseudo Relevance Feedback (PRF) is effective for handling clinical jargon in EHR but often overlooks term importance and co-occurrence.
- Existing PRF models fail to consider both term importance and co-occurrence relationships in feedback documents.
Purpose of the Study:
- To develop an improved information retrieval model for clinical settings by integrating EHR data with biomedical literature.
- To propose a novel approach that considers both term importance and proximity in query expansion.
- To enhance the effectiveness of retrieving clinical support documents for medical professionals.
Main Methods:
- Incorporated the original HAL model into Rocchio's model to create a HAL-based Rocchio's model (HRoc) for query expansion.
- Introduced a new concept of term proximity feedback weight to better leverage co-occurrence information.
- Designed three normalization methods and an adaptive parameter for optimizing proximity information integration and window size selection.
Main Results:
- The HRoc and HRoc_AP models outperformed advanced models like PRoc2 and TF-PRF on the 2016 TREC Clinical Support medicine dataset.
- Achieved an 8.5% and 12.24% increase in Mean Average Precision (MAP) compared to PRoc2 and TF-PRF, respectively.
- Demonstrated a 7.86% and 9.88% increase in F1 score compared to PRoc2 and TF-PRF, respectively.
Conclusions:
- The HRoc model effectively enhances the precision and recall rate of information retrieval for clinical support documents.
- The HRoc_AP model, with its self-adaptive parameter, reduces hyper-parameters while maintaining performance, improving efficiency and applicability.
- The proposed models assist clinicians in effectively retrieving relevant clinical support information, aiding decision-making.
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