Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chronic Kidney Disease I: Introduction01:25

Chronic Kidney Disease I: Introduction

509
Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
509
Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

491
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
491
Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

298
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
298
Chronic Kidney Disease IV: Nursing Management01:18

Chronic Kidney Disease IV: Nursing Management

253
Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care​.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of...
253
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

330
Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
330
Urinary Tract Calculi I: Introduction01:28

Urinary Tract Calculi I: Introduction

359
Renal calculi, or kidney stones, are solid deposits of minerals and salts formed inside the kidneys. In medical terminology, "calculus" refers to the stone itself, while "lithiasis" describes the process of stone formation. Depending on their location within the urinary system, these stones may be classified as either urolithiasis, when situated within the urinary tract, or nephrolithiasis, when located within the kidneys. Each term signifies the specific impact of the stone.Predisposition...
359

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Lower AKI Risk and Higher Survival With Microaxial Flow Pump Support During Elective PCI: A Propensity Score-Matched Study.

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions·2026
Same author

[Lumbar disc herniation].

Orthopadie (Heidelberg, Germany)·2026
Same author

When Protection Turns Pathogenic: Dual Compartment Functions of Myeloid YB-1 in Renal IRI.

International journal of molecular sciences·2026
Same author

Pathway-centric visualization of cell-cell communication in single-cell transcriptomics data.

NPJ systems biology and applications·2026
Same author

Cell-specific Y-box-binding protein-1 drives liver-kidney injury in cholestasis.

American journal of physiology. Renal physiology·2026
Same author

[Skin manifestations in orthopedic diseases (notalgia paresthetica and brachioradial pruritus)].

Orthopadie (Heidelberg, Germany)·2026

Related Experiment Video

Updated: Jan 2, 2026

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation
08:43

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation

Published on: May 31, 2016

20.1K

Valvular Calcification in Chronic Kidney Disease.

Vincent M Brandenburg1, Alexander Schuh2, Rafael Kramann3

  • 1Department of Cardiology and Nephrology, Rhein-Maas Klinikum, Würselen, Germany.

Advances in Chronic Kidney Disease
|December 14, 2019
PubMed
Summary

Patients with chronic kidney disease (CKD) experience accelerated cardiovascular calcification, particularly aortic valve stenosis. This calcification significantly impacts morbidity and mortality, necessitating close monitoring and timely intervention for renal patients.

Keywords:
AfterloadCalcific aortic stenosisHeart valvesLeft ventricular hypertrophyTranscatheter aortic valve implantationVitamin K

More Related Videos

A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro
11:30

A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro

Published on: June 2, 2022

2.3K
Analysis of Extracellular Vesicle-Mediated Vascular Calcification Using In Vitro and In Vivo Models
09:01

Analysis of Extracellular Vesicle-Mediated Vascular Calcification Using In Vitro and In Vivo Models

Published on: January 27, 2023

2.0K

Related Experiment Videos

Last Updated: Jan 2, 2026

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation
08:43

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation

Published on: May 31, 2016

20.1K
A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro
11:30

A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro

Published on: June 2, 2022

2.3K
Analysis of Extracellular Vesicle-Mediated Vascular Calcification Using In Vitro and In Vivo Models
09:01

Analysis of Extracellular Vesicle-Mediated Vascular Calcification Using In Vitro and In Vivo Models

Published on: January 27, 2023

2.0K

Area of Science:

  • Cardiovascular Medicine
  • Nephrology
  • Valvular Heart Disease

Background:

  • Accelerated cardiovascular calcification is common in chronic kidney disease (CKD) and end-stage renal disease (ESRD).
  • Cardiovascular calcification, especially at the aortic valve, drives morbidity and mortality in renal patients.
  • Calcific aortic stenosis (CAS) is the most prevalent valvular heart disease and is highly prevalent in CKD/ESRD patients.

Purpose of the Study:

  • To highlight the significant link between CKD/ESRD and calcific aortic stenosis.
  • To emphasize the prognostic importance of aortic valve calcification in renal patients.
  • To discuss current and novel therapeutic strategies for CAS in the context of CKD/ESRD.

Main Methods:

  • Review of existing literature on cardiovascular calcification in CKD/ESRD.
  • Analysis of the correlation between aortic valve calcification and stenosis severity.
  • Evaluation of treatment options for CAS in renal patients.

Main Results:

  • The degree of aortic valve calcification directly predicts the severity of stenosis.
  • CAS contributes to left ventricular hypertrophy in CKD/ESRD patients.
  • Limited medical options exist for preventing CAS progression; surveillance and valve replacement are key.

Conclusions:

  • CAS is a critical complication in CKD/ESRD, worsening patient outcomes.
  • Timely intervention, including valve replacement, is crucial for managing CAS in renal disease.
  • Transcatheter aortic valve implantation presents a challenging but promising option for frail patients with advanced CKD/ESRD and CAS.