An alternative model for additive and cytoplasmic genetic and maternal effects on lactation
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Updated: Oct 9, 2026

Evaluation of Mammary Gland Development and Function in Mouse Models
Published on: July 21, 2011
1Department of Meat and Animal Science, University of Wisconsin-Madison, 53706.
Abstract:
Results from a recent study that presented evidence suggesting a lack of cytoplasmic inheritance of lactation traits were reexamined using a model that included effects of additive genotype, cytoplasmic genotype, their interaction, and maternal influences. Under this model, equivalent estimates of heritability from daughter-dam and grand-daughter-grand-dam regression that exceed those from paternal half-sib correlation were consistent with the presence of cytoplasmic inheritance. A definitive answer to the question of cytoplasmic inheritance of lactation traits awaits a designed experiment, likely employing transfer of identical nuclei into varying cytoplasmic backgrounds.
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