Frequency of Listeria monocytogenes Isolated from Diarrhea Samples of Pediatric Patients at Central Iran

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Elnaz Abbasi1,2, Alireza Amouzandeh-Nobaveh1, Ehsanollah Ghaznavi-Rad1,3

  • 1Department of Microbiology & Immunology, Faculty of Medicine, Arak University of Medical Sciences.

Reports of Biochemistry & Molecular Biology
|December 14, 2019
PubMed
Abstract

Insights

Listeria monocytogenes infections are rare in Iranian children with diarrhea, with only 4.6-5.2% of samples testing positive. Most infections occurred in children under five, indicating a low prevalence in this age group.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Pediatrics

Background:

  • Listeria monocytogenes is a foodborne pathogen causing gastroenteritis.
  • Its prevalence in pediatric diarrheal disease in Iran is not well-defined.
  • This study addresses this knowledge gap in the Iranian pediatric population.

Purpose of the Study:

  • To determine the frequency of Listeria monocytogenes in pediatric infectious diarrhea cases in Iran.
  • To assess the role of this pathogen in childhood diarrhea in the region.

Main Methods:

  • A cross-sectional study of 173 infectious diarrhea samples from pediatric patients in Arak, Iran.
  • Samples were analyzed using Listeria Enrichment Broth Base and Listeria Selective Agar.
  • Polymerase Chain Reaction (PCR) targeting the InlA gene was used as a confirmatory method.

Main Results:

  • Listeria monocytogenes was identified in 4.6% of samples by culture and 5.2% by PCR.
  • The majority of positive cases (77.7%) were in children younger than five years old.
  • Overall prevalence was low in the studied pediatric population.

Conclusions:

  • Listeria monocytogenes exhibits a low prevalence as a cause of diarrhea in children in central Iran.
  • Findings suggest this pathogen is not a common cause of infectious diarrhea in this demographic.
  • Pediatricians should consider this low prevalence when diagnosing and treating intestinal diseases in children in this region.
Keywords:
Listeria monocytogenesDiarrheaIranPediatric

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