Related Experiment Video
Updated: Jan 2, 2026
10:39
3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
18.6K
Personality profile and depression in migraine: a meta-analysis
Federica Garramone1, Chiara Baiano1, Antonio Russo2
1Department of Psychology, University of Campania "Luigi Vanvitelli", Caserta, Italy.
Summary
Migraine is linked to specific personality traits like high neuroticism and low extraversion. Neuroticism, a key trait, influences depression severity in migraine patients, suggesting early personality assessment for at-risk individuals.
Area of Science:
- Neuroscience
- Psychiatry
- Genetics
Background:
- Psychological factors significantly impact migraine, yet their connection with personality traits and depression remains under-explored.
- Understanding these links is crucial for comprehensive migraine management.
Purpose of the Study:
- To identify the distinct personality profile of individuals with migraine.
- To investigate the relationship between personality traits and depression in migraineurs versus non-migraineurs.
Main Methods:
- A systematic literature search was conducted across PsycInfo, PubMed, and Scopus databases up to March 2019.
- Sixteen relevant primary studies were included in a meta-analysis.
Main Results:
- Migraineurs exhibited higher Harm Avoidance, Persistence, and lower self-directedness (Psychobiological Model).
- Migraineurs showed higher neuroticism and lower extraversion (Three Factor Model).
- Meta-regression indicated neuroticism moderates the depression-migraine relationship.
Conclusions:
- Migraine is associated with a specific personality profile, notably high neuroticism.
- Neuroticism influences depression severity in migraineurs.
- Early personality trait evaluation may identify individuals prone to migraine-associated psychopathology.
Related Concept Videos
01:27Depressive Disorders: Etiology
387
Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
387
01:27Depressive Disorders: MDD and Dysthymia
521
Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
521
01:18Depression: Overview
713
Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
713
01:23Antidepressant Drugs: MAOIs and Other Agents
724
Atypical antidepressants, including bupropion (Wellbutrin), mirtazapine (Remeron), nefazodone (Serzone), trazodone (Desyrel), and vilazodone (Viibryd), offer unique mechanisms of action. Bupropion weakly inhibits dopamine and norepinephrine reuptake, aiding depression treatment and smoking cessation, with a low risk of sexual dysfunction. Mirtazapine enhances serotonin and norepinephrine neurotransmission, leading to sedation, increased appetite, and weight gain. As a result, it helps treat...
724
01:23Stress Prevention and Stress Management Techniques II
457
Personality types, particularly Type A and Type B, significantly influence how individuals respond to stress. These personality distinctions are marked by varying levels of ambition, competitiveness, and coping styles, all of which shape an individual's resilience to stressors.
Type A Personality: Driven and Easily Stressed
Individuals with Type A personalities are often highly competitive and ambitious and operate with a strong sense of urgency. Commonly labeled as...
Type A Personality: Driven and Easily Stressed
Individuals with Type A personalities are often highly competitive and ambitious and operate with a strong sense of urgency. Commonly labeled as...
457
01:22Self-Report Tests of Personality
713
Self-report inventories are objective personality assessments that use multiple-choice items or numbered scales, typically ranging from 1 (strongly disagree) to 5 (strongly agree). They are often called Likert scales after Rensis Likert. These inventories are widely used due to their ease of administration and cost-effectiveness. One of the most prominent examples is the Minnesota Multiphasic Personality Inventory (MMPI), initially developed in the 1940s to assess abnormal personality traits.
713