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Ocular Surface Disease in a PICU: Incidence and Outcomes With a Dynamic Eye Care Protocol
Angela Niemi1, Brooke E Geddie2, Surender Rajasekaran3
1Michigan State University College of Human Medicine, Grand Rapids, MI.
Insights
Sedated pediatric intensive care patients are at risk for ocular surface disease. A standardized eye care protocol significantly reduced the incidence of corneal issues in these vulnerable children.
Area of Science:
- Pediatric Critical Care Medicine
- Ophthalmology
- Ocular Surface Disease
Background:
- Sedated intensive care patients have impaired ocular protective mechanisms, increasing risk for ocular surface disease and potential vision loss.
- Historically, routine eye care was limited to critically ill patients receiving neuromuscular blockade.
Purpose of the Study:
- Determine the occurrence rate of ocular surface disease in sedated and ventilated children.
- Identify risk factors for ocular surface disease.
- Assess the progression of ocular injury with a routine eye care protocol.
Main Methods:
- Prospective cohort study in a tertiary care medical-surgical Pediatric Intensive Care Unit (PICU).
- Evaluated 479 intubated patients over 19 months, performing 1,242 corneal exams.
- Implemented staff education and a standardized PICU eye care protocol, adjusting frequency based on ocular condition.
Main Results:
- 15% of patients had ocular surface disease on admission; incidence rose to 32.2% during hospitalization before protocol adjustments.
- Trauma patients and those intubated prehospital or in the ED had higher initial incidence.
- The standardized protocol decreased overall ocular surface disease incidence to 8.6% by the last examination, preventing severe complications.
Conclusions:
- Ocular surface disease is under-recognized in critically ill pediatric patients.
- A standardized, dynamic eye care protocol can improve corneal health.
- Improved corneal health may reduce injury, pain, infection, and long-term vision loss in pediatric ICU patients.
Objectives:
Sedated intensive care patients have impaired ocular protective mechanisms putting them at risk for ocular surface disease with potential vision loss. Historically, routine eye care has been limited to critically ill patients receiving neuromuscular blockade. The aim of this project was to determine the occurrence rate of ocular surface disease in sedated and ventilated children, identify risk factors, and determine the progression of injury with routine eye care.
Design:
Prospective cohort study.
Setting:
A tertiary care medical-surgical PICU.
Patients:
All intubated patients admitted from May 2015 to December 2016.
Interventions:
Staff education regarding corneal examination with fluorescein, and routine eye care as per a PICU eye care protocol.
Measurements And Main Results:
We evaluated 479 patients (1,242 corneal exams) and found that 15% had ocular surface disease at admission to the PICU: keratopathy 62, abrasion 16. The highest incidence was in trauma patients (39.0%) and those intubated in the emergency department (22.2%) or prehospital setting (42.9%). Of the 245 patients with multiple ocular assessments, 32.2% displayed ocular surface disease at some point during their hospitalization: keratopathy 73, abrasion 24. Ourprotocol dictated increased frequency of eye care if ocular surface disease worsened. As a result, the overall incidence of ocular surface disease decreased to 8.6% by the last examination (keratopathy 19, mild abrasion 2), but more severe ocular abnormalities such as corneal infiltrates, ulcers, or scarring were not observed. Based on multivariate analysis, clinical factors associated with increased risk of ocular surface disease included primary diagnosis, and lagophthalmos (incomplete eyelid closure).
Conclusions:
Ocular surface disease is an under-recognized process in critically ill pediatric patients. A standardized and dynamic protocol may improve corneal health, which in turn may reduce injury, pain, infection, and long-term vision loss.
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