Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Know your cholesterol: population screening.

P Laemmle1, L Unger, C McCray

  • 1Laboratory Services, Jewish Hospital, Cincinnati, OH 45229.

The Journal of Laboratory and Clinical Medicine
|November 1, 1988
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Maturity and its relationship to plasma lipid and lipoprotein levels in adolescents: The Fels longitudinal study.

American journal of human biology : the official journal of the Human Biology Council·2017
Same author

The Effects of Physical Training on Blood Lipid Profiles in Adolescents With Insulin-Dependent Diabetes Mellitus.

The Physician and sportsmedicine·2016
Same author

A polymorphism linked to bipolar affective disorder does not alter the CRE activity of constitutively activated trace amine receptor 4.

Molecular psychiatry·2007
Same author

Metformin-diet ameliorates coronary heart disease risk factors and facilitates resumption of regular menses in adolescents with polycystic ovary syndrome.

Journal of pediatric endocrinology & metabolism : JPEM·2006
Same author

[Rheumatoid arthritis at the cervical spine -- an underestimated problem].

Deutsche medizinische Wochenschrift (1946)·2005
Same author

Amaurosis fugax: associations with heritable thrombophilia.

Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·2005
Same journal

Studies on streptomycin; assay in body fluids.

The Journal of laboratory and clinical medicine·2010
Same journal

Gastrocolic fistula; an experimental study.

The Journal of laboratory and clinical medicine·2010
Same journal

An isolated heart perfusion system adapted to the determination of nongaseous metabolities; with sample data upon the isolated monkey heart.

The Journal of laboratory and clinical medicine·2010
Same journal

A new type of glass cage for metabolism studies.

The Journal of laboratory and clinical medicine·2010
Same journal

A simple electrocardiograph contact electrode for use with the smaller laboratory animal.

The Journal of laboratory and clinical medicine·2010
Same journal

A primary standard for the colorimetric determination of hemoglobin.

The Journal of laboratory and clinical medicine·2010
See all related articles

Nonfasting venous blood tests for total cholesterol are effective and practical for identifying individuals at moderate to high risk for heart disease. This method offers a cost-effective approach to cholesterol screening for the general adult population.

Area of Science:

  • Cardiovascular Disease Prevention
  • Public Health Screening
  • Biochemical Analysis

Background:

  • Elevated total serum cholesterol is a significant risk factor for coronary heart disease.
  • Widespread knowledge of cholesterol levels is a public health goal.
  • Current screening methods may have barriers to accessibility and cost.

Purpose of the Study:

  • To assess the effectiveness, practicality, and cost of using nonfasting venous blood samples for total cholesterol measurement.
  • To compare results from nonfasting venous blood samples with capillary blood samples.
  • To evaluate the utility of mailed results for cholesterol screening.

Main Methods:

  • Analysis of total cholesterol levels from 3844 nonfasting self-referred subjects using venous blood with mailed results.

Related Experiment Videos

  • Comparison with 1167 subjects using capillary blood with immediate results.
  • Application of consensus-defined cut points for moderate and high coronary heart disease risk based on age.

    • Main Results:

    • 45% of the venous cohort and 37% of the capillary cohort fell into moderate- or high-risk cholesterol ranges.
    • Median venous and capillary total cholesterol values were higher than historical fasting data, potentially due to nonfasting status, serum vs. plasma, and self-referral bias.
    • Cost per subject was $5.09 (venous) and $7.12 (capillary), with higher costs for at-risk individuals.

    Conclusions:

    • Nonfasting venous blood sampling is a viable and cost-effective method for population-based cholesterol screening.
    • The method effectively identifies individuals requiring further assessment and follow-up.
    • Emphasis on resampling with fasting and follow-up is crucial for accurate risk assessment and management.