Biochemical studies of the chicken vitreous in light-induced avian glaucoma

Changes in several macromolecular species of the vitreous are traced during post-hatching development in normal and glaucomatous avian eyes. 1. Total gel vitreous, and its hydroxyproline content, change little during development. 2. Sol vitreous increases parallel eye growth, the concentrations of hexosamine and hexuronic acid remaining constant. 3. In light-induced avian glaucoma, the sol, but not the gel, is further increased, although the hyaluronic acid components are not diluted in the pathologically enlarged eye.