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Species-related difference in calcium accumulation by cardiac mitochondria
H G Sachs1, J A Colgan, M L Lazarus
1Department of Anatomy, University of Illinois, Chicago 60612.
Abstract:
1. Mitochondria isolated from the ventricles of Cavia porcellus, Mesocricetus auratus, Rattus rattus and Mus musculus accumulate calcium in an energy-linked process. 2. Measurements of the initial velocity of accumulation by dual-wavelength spectrophotometry show species-dependent variation, with Cavia demonstrating the fastest rate and Rattus the slowest rate of accumulation. 3. Total amount of calcium accumulated per unit protein varied in a manner similar to rate of accumulation, with Cavia accumulating the greatest amount of calcium and Rattus the least.