Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

272
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
272
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

284
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
284
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

247
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
247
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

222
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
222
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

13.2K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
13.2K
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

773
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
773

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Is cellular senescence a biological feature of Long COVID? A transcriptomic analysis across comparative post-acute sequelae phenotypes.

The Journal of infectious diseases·2026
Same author

Host Genetic Regulation of NLRP3 Inflammasome Cytokines Reveals Immune and Vascular Pathways in HIV.

medRxiv : the preprint server for health sciences·2026
Same author

EXPRESS: The Association of Hidradenitis Suppurativa with Increased Risk of Systemic Infections in End-stage Renal Disease.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research·2026
Same author

Correction: SARS-CoV-2 infection is associated with self-reported post-acute neuropsychological symptoms within six months of follow-up.

PloS one·2026
Same author

Nail changes associated with mortality in end-stage renal disease: A national retrospective cohort study.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research·2026
Same author

Influenza-like illness in cigarette smokers and electronic-cigarette users: a secondary analysis from the PAIVED study.

Frontiers in public health·2026
Same journal

Providers' Perspectives on Hospital-Based Tobacco Treatment Efforts.

The American journal of the medical sciences·2026
Same journal

In Memoriam: Maurice A. Mufson, MD, MACP.

The American journal of the medical sciences·2026
Same journal

Outcomes of acute myeloid leukemia patients admitted to the intensive care unit within 100 days of allogeneic hematopoietic stem cell transplantation.

The American journal of the medical sciences·2026
Same journal

Association Between Reverse Triiodothyronine and Cardiac Complications in Patients with Uncontrolled Graves' Disease.

The American journal of the medical sciences·2026
Same journal

Chlorthalidone vs. hydrochlorothiazide in hypertension management: Lessons for guiding clinical practice.

The American journal of the medical sciences·2026
Same journal

The impact of COVID-19 on alcohol-associated hepatitis and alcohol-associated cirrhosis.

The American journal of the medical sciences·2026
See all related articles

Related Experiment Video

Updated: Jan 1, 2026

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
07:13

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Published on: April 12, 2021

4.8K

Risk Factors Associated With Invasive Fungal Infections in Kidney Transplant Patients.

Sara Leitheiser1, Andrew Harner2, Jennifer L Waller3

  • 1Department of Medicine, Medical College of Georgia at Augusta University, Augusta, GA.

The American Journal of the Medical Sciences
|December 15, 2019
PubMed
Summary
This summary is machine-generated.

Kidney transplant patients face a higher risk of invasive fungal infections (IFI). Key risk factors include older age, diabetes, bacterial pneumonia, and urinary tract infections, informing diagnosis and treatment.

Keywords:
InfectionsInvasive fungal infectionKidney transplantationRisk factors

More Related Videos

An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract
07:42

An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract

Published on: July 1, 2020

5.7K
TBase - an Integrated Electronic Health Record and Research Database for Kidney Transplant Recipients
09:00

TBase - an Integrated Electronic Health Record and Research Database for Kidney Transplant Recipients

Published on: April 13, 2021

5.1K

Related Experiment Videos

Last Updated: Jan 1, 2026

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
07:13

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Published on: April 12, 2021

4.8K
An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract
07:42

An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract

Published on: July 1, 2020

5.7K
TBase - an Integrated Electronic Health Record and Research Database for Kidney Transplant Recipients
09:00

TBase - an Integrated Electronic Health Record and Research Database for Kidney Transplant Recipients

Published on: April 13, 2021

5.1K

Area of Science:

  • Nephrology
  • Infectious Diseases
  • Immunology

Background:

  • Kidney transplant recipients (KTRs) are a vulnerable population with an elevated risk of invasive fungal infections (IFI).
  • Understanding specific risk factors is crucial for preventing and managing IFI in KTRs.

Purpose of the Study:

  • To identify demographic, clinical, and medication-associated risk factors for IFI in kidney transplant recipients.
  • To analyze the incidence and types of IFI in KTRs using a large national database.

Main Methods:

  • Retrospective analysis of the United States Renal Data System (USRDS) database.
  • Inclusion of kidney transplant patients who underwent transplantation between 2005 and 2008.
  • Identification of IFI cases using ICD-9 codes and categorization into specific fungal groups (Candida, Histoplasmosis, Aspergillosis, Cryptococcosis, Other mycoses).
  • Statistical modeling to determine relative risks (RR) and adjusted relative risks (aRR) for various factors.

Main Results:

  • A total of 57,188 KTRs were analyzed, with 1,218 experiencing 1,343 IFI diagnoses (median time to infection: 495 days).
  • The most common IFI types were "Other" mycoses (37%) and Aspergillosis (22%).
  • Increased risk for any IFI was associated with age ≥65 years. Top clinical risk factors included diabetes (aRR=1.71), bacterial pneumonia (aRR=1.62), and urinary tract infection (UTI) (aRR=1.34).
  • Mycophenolate mofetil use was linked to a reduced risk of candidemia.

Conclusions:

  • IFI risk in KTRs is multifactorial, influenced by demographics, comorbidities, and specific fungal pathogens.
  • Identifying these risk factors provides a clinical profile to guide the diagnosis and presumptive treatment of IFI in this high-risk population.