Related Experiment Video
Updated: Jan 1, 2026

BioMEMS: Forging New Collaborations Between Biologists and Engineers
Published on: November 1, 2007
Collaborating constructively for sustainable biotechnology
Nicholas E Matthews1,2,3, Carrie A Cizauskas4, Donovan S Layton4
1Manchester Institute of Innovation Research, Alliance Manchester Business School, The University of Manchester, Booth Street West, Manchester, M15 6PB, UK. n.matthews@manchester.ac.uk.
Biotechnology offers sustainable alternatives to fossil fuels, but assessing trade-offs is crucial. Constructive Sustainability Assessment helps companies proactively address environmental and social impacts of bio-based products like nylon.
Area of Science:
- Biotechnology and synthetic biology for sustainable chemical and material production.
- Environmental science and life cycle assessment methodologies.
- Social science and constructive technology assessment frameworks.
Background:
- Societal needs demand novel technologies for sustainability.
- Biotechnology, particularly synthetic biology, presents bio-based alternatives to fossil-derived products.
- The sustainability of biotechnological solutions requires careful evaluation due to potential trade-offs.
Purpose of the Study:
- To assess the sustainability capacity of bio-based nylon production.
- To apply a Constructive Sustainability Assessment framework using deliberative and analytical methods.
- To demonstrate a collaborative approach for early-stage consequence anticipation and design modification.
Main Methods:
- Utilized a framework of Constructive Sustainability Assessment.
- Employed both deliberative and analytical approaches.
- Focused on the specific case of bio-based nylon production.
Main Results:
- Identified potential for life cycle carbon dioxide (CO2) and nitrous oxide (N2O) savings with bio-based processes.
- Reported mixed results across other environmental and social impact categories.
- Demonstrated collaborative knowledge generation for early-stage impact assessment.
Conclusions:
- Bio-based nylon shows promise for CO2 and N2O reduction but requires evaluation of other impacts.
- Collaborative and early-stage assessment is key to anticipating and mitigating sustainability consequences.
- The demonstrated approach enables technological developers to better understand and respond to product sustainability implications.
Related Concept Videos
Plant Breeding and Biotechnology
Synthetic Biology
Golden rice
Golden rice is a genetically modified...
Bioremediation
Biodiversity and Human Values
Recombinant DNA
Transgenic Plants
The first-ever transgenic plant was a tobacco plant developed in 1983 that showed resistance against the tobacco mosaic virus. Since then, many transgenic plants have been developed and commercialized for improving the agricultural, ornamental, and horticultural value of a crop plant. Transgenic...

