Related Experiment Video
Updated: Jan 1, 2026
06:06
Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint
Published on: July 22, 2021
6.7K
Recent updates on worldwide gout epidemiology
Camilla Mattiuzzi1, Giuseppe Lippi2
1Service of Clinical Governance, Provincial Agency for Social and Sanitary Services, Trento, Italy.
Clinical Rheumatology
|December 15, 2019
Summary
Gout cases and health loss have significantly increased globally over 25 years, particularly in men and high socioeconomic status regions. Mortality is projected to rise by 55% by 2060.
Area of Science:
- Epidemiology
- Public Health
- Rheumatology
Background:
- Gout, a form of inflammatory arthritis, poses a significant global health challenge.
- Recent epidemiological data indicate a concerning rise in gout incidence, prevalence, and associated health loss.
Purpose of the Study:
- To present current statistics and future projections for worldwide gout epidemiology.
- To analyze trends in gout's burden concerning demographics and socioeconomic factors.
Main Methods:
- Data were sourced from the Global Health Data Exchange (GHDx) registry.
- Projected mortality data were obtained from the World Health Organization (WHO) database.
Main Results:
- In 2017, an estimated 41.22 million people had gout globally (0.54% prevalence), with 7.44 million new cases (0.097% incidence), causing 1.28 million disability-adjusted life years (DALYs).
- Gout's incidence, prevalence, and health loss have increased over the past 25 years, disproportionately affecting men.
- Gout burden correlates with aging and socioeconomic status, with over a 3-fold higher risk in high Socio-Demographic Index (SDI) regions compared to low SDI regions.
Conclusions:
- The epidemiologic burden of gout remains substantial worldwide and is unlikely to decrease soon.
- Gout disproportionately affects men and individuals in high SDI countries.
- Gout mortality is projected to increase by 55% by 2060, highlighting the need for effective public health interventions.
More Related Videos
Related Concept Videos
01:11Genome-wide Association Studies-GWAS
15.2K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
GWAS does not require the identification of the target gene involved in...
15.2K
01:08Prevalence and Incidence
1.4K
In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
1.4K
01:26Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
331
Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
331
01:23Gastritis III: Clinical Manifestations and Management
1.1K
The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
1.1K
01:27Gastritis-I: Introduction and Types
2.0K
Gastritis, defined by the inflammation or irritation of the stomach lining or gastric mucosa, manifests in several distinct forms: acute, chronic, reactive, and a specific subtype known as autoimmune metaplastic atrophic gastritis.
Acute gastritis presents as a sudden inflammation triggered by various stressors to the stomach lining, such as exposure to corrosive agents, local irritants like aspirin and other NSAIDs, alcohol consumption, radiation therapy, physical trauma, severe burns, sepsis,...
Acute gastritis presents as a sudden inflammation triggered by various stressors to the stomach lining, such as exposure to corrosive agents, local irritants like aspirin and other NSAIDs, alcohol consumption, radiation therapy, physical trauma, severe burns, sepsis,...
2.0K
01:29Gastroesophageal Reflux Disease II: Clinical Features and Management
624
Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
624