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Advanced Heart Failure in Adults With Congenital Heart Disease

Jonathan N Menachem1, Kelly H Schlendorf1, Jeremy A Mazurek2

  • 1Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.

JACC. Heart Failure
|December 16, 2019
PubMed

Insights

Improved care means more adults with congenital heart disease (CHD) survive, but heart failure (HF) remains a major threat. Further research is needed to improve treatments and outcomes for adults with CHD.

Area of Science:

  • Cardiology
  • Adult Congenital Heart Disease
  • Heart Failure

Background:

  • Survival rates for children with congenital heart disease (CHD) have significantly improved, with over 90% now expected to reach adulthood.
  • Heart failure (HF) is the primary cause of mortality among adults with CHD.
  • Despite advances in recognition and treatment, challenges persist in managing adult CHD patients.

Purpose of the Study:

  • To highlight the current state of care for adults with CHD.
  • To identify key challenges and areas for future investigation in managing heart failure in this population.
  • To underscore the importance of continued research for improving long-term outcomes.

Main Methods:

  • Review of current literature and clinical practices regarding adult CHD.
  • Analysis of mortality data focusing on heart failure as a cause of death.
  • Discussion of emerging treatment modalities including heart transplantation and mechanical circulatory support.

Main Results:

  • Adults with CHD represent a growing population with unique cardiovascular needs.
  • Heart failure is a critical and often fatal complication in this demographic.
  • Advanced interventions like heart transplantation and mechanical support are viable options but require further optimization.

Conclusions:

  • Continued advancements in medical and surgical interventions are crucial for improving the quality of life and survival rates for adults with CHD.
  • Further research is essential to address the complexities of heart failure management in adult CHD patients.
  • Optimizing care pathways and exploring novel therapeutic strategies are necessary to overcome existing challenges.

Keywords:
ACHDcongenitalhearttransplantventricular assist device

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