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Doxycycline-induced hemorrhagic esophagitis: a pediatric case
1Department of Pediatrics, Iwaki Kyoritsu General Hospital, Japan.
Journal of Pediatric Gastroenterology and Nutrition
|September 1, 1988
Insights
Medication-induced esophagitis is rare in children. This case highlights hemorrhagic esophagitis from doxycycline tablets, emphasizing consideration of drug-induced esophagitis in pediatric patients taking oral medications.
Area of Science:
- Pediatric Gastroenterology
- Pharmacology
- Clinical Medicine
Background:
- Medication-induced esophagitis is a known adverse effect in adults.
- It is infrequently reported in the pediatric population.
- Understanding the pathophysiology is crucial for diagnosis and management.
Observation:
- A pediatric case of hemorrhagic esophagitis is presented.
- The condition was directly linked to the ingestion of doxycycline tablets.
- This highlights a specific instance of drug-induced esophageal injury.
Findings:
- Doxycycline tablets can cause severe esophageal inflammation and bleeding in children.
- The pathophysiology involves direct mucosal injury from the medication.
- Prompt recognition is key to preventing complications.
Implications:
- Pediatricians and healthcare providers should consider medication-induced esophagitis in children presenting with esophageal symptoms.
- Awareness of this adverse effect is critical when prescribing oral medications, especially tablets and capsules, to pediatric patients.
- This case underscores the need for careful medication review in pediatric gastrointestinal cases.
Abstract:
Esophagitis induced by medications has been recognized in adults but rarely in children. A child with hemorrhagic esophagitis resulting from taking doxycycline tablets for treatment is described and the pathophysiology of this condition is discussed. In pediatric cases treated by tablets or capsules, the possibility of medication-induced esophagitis should always be considered.