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Doxycycline-induced hemorrhagic esophagitis: a pediatric case
1Department of Pediatrics, Iwaki Kyoritsu General Hospital, Japan.
Journal of Pediatric Gastroenterology and Nutrition
|September 1, 1988
Summary
Medication-induced esophagitis is rare in children. This case highlights hemorrhagic esophagitis from doxycycline tablets, emphasizing consideration of drug-induced esophagitis in pediatric patients taking oral medications.
Area of Science:
- Pediatric Gastroenterology
- Pharmacology
- Clinical Medicine
Background:
- Medication-induced esophagitis is a known adverse effect in adults.
- It is infrequently reported in the pediatric population.
- Understanding the pathophysiology is crucial for diagnosis and management.
Observation:
- A pediatric case of hemorrhagic esophagitis is presented.
- The condition was directly linked to the ingestion of doxycycline tablets.
- This highlights a specific instance of drug-induced esophageal injury.
Findings:
- Doxycycline tablets can cause severe esophageal inflammation and bleeding in children.
- The pathophysiology involves direct mucosal injury from the medication.
- Prompt recognition is key to preventing complications.
Implications:
- Pediatricians and healthcare providers should consider medication-induced esophagitis in children presenting with esophageal symptoms.
- Awareness of this adverse effect is critical when prescribing oral medications, especially tablets and capsules, to pediatric patients.
- This case underscores the need for careful medication review in pediatric gastrointestinal cases.