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Improved Registration of 3D CT Angiography with X-ray Fluoroscopy for Image Fusion During Transcatheter Aortic Valve Implantation
Published on: June 3, 2018
Computed Tomography Features of Cuspal Thrombosis and Subvalvular Tissue Ingrowth after Transcatheter Aortic Valve
Hyun Jung Koo1, Jooae Choe1, Do-Yoon Kang2
1Department of Radiology and Research Institute of Radiology, Cardiac Imaging Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Insights
Post-transcatheter aortic valve implantation (TAVI) CT scans reveal common findings like hypoattenuating subvalvular thickening (HAST) and hypoattenuating leaflet thickening (HALT). Longer implant duration, hypertension, and HAST are linked to HALT after TAVI.
Area of Science:
- Cardiology
- Radiology
- Medical Imaging
Background:
- Post-transcatheter aortic valve implantation (TAVI) computed tomography (CT) findings require further elucidation beyond hypoattenuating leaflet thickening (HALT).
- Understanding cardiac CT findings after TAVI is crucial for patient management and assessing valve performance.
Purpose of the Study:
- To describe cardiac CT findings following TAVI.
- To investigate factors associated with hypoattenuating leaflet thickening (HALT).
Main Methods:
- Retrospective analysis of post-TAVI cardiac CT scans from 138 patients.
- Review of CT findings including hypoattenuating subvalvular thickening (HAST), sinus of Valsalva thrombus, HALT, and leaflet motion limitation.
- Logistic regression analysis to identify factors associated with HALT.
Main Results:
- HAST (23%) and HALT (18%) were common findings on post-TAVI CT.
- TAVI device implant duration (OR 1.5), hypertension (OR 0.2), and HAST (OR 4.9) were significantly associated with HALT.
- Longer implant durations were observed in patients with HAST, HALT, or leaflet motion limitation.
Conclusions:
- Cardiac CT demonstrates various findings after TAVI, including HAST, HALT, thrombus, and leaflet motion abnormalities.
- Implant duration, hypertension, and HAST are significant predictors of HALT.
- These findings aid in the comprehensive assessment of TAVI outcomes using cardiac CT.
Abstract:
Post-transcatheter aortic valve implantation (TAVI) computed tomography (CT) findings have not been fully elucidated, except hypoattenuating leaflet thickening (HALT). The objective of this study was to describe cardiac CT findings after TAVI, and investigate factors associated with HALT. This retrospective study included patients who underwent TAVI and post-TAVI cardiac CT scans. On CT, abnormal findings such as hypoattenuating subvalvular thickening (HAST), thrombus within the sinus of Valsalva, HALT, and leaflet motion limitation were thoroughly reviewed. Clinical and CT findings were compared between patients with HALT and those without HALT. Logistic regression analysis was performed to determine factors associated with HALT. A total of 138 patients (64 male, mean 78.5 ± 5.2 years of age) with post-TAVI CT scans were included. The median duration from TAVI to CT was 17.5 days (interquartile range, 3 to 390.8 days). HAST and thrombus within the sinus of Valsalva were detected in 32 (23%) and 5 (4%) patients, respectively. HALT and leaflet motion limitations were found in 25 (18%) and 20 (14%) of patients, respectively. Pannus was diagnosed in 2 patients. TAVI device implant duration (odds ratio [OR], 1.5; p = 0.01), hypertension (OR, 0.2; p = 0.03), and HAST (OR, 4.9; p = 0.003) were associated with HALT. Implant durations were longer in patients with HAST, HALT, or leaflet motion limitation (p < 0.05, for all). In conclusion, HAST, HALT, thrombus within the sinus of Valsalva, and leaflet motion limitation are not uncommon after TAVI. Implant duration, hypertension, and HAST are associated with HALT.
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